Clinical outcomes of transcatheter aortic valve implantation (TAVI) in nonagenarians from the optimized catheter valvular intervention<scp>‐</scp>TAVI registry

Noguchi, Masahiko; Tabata, Minoru; Obunai, Kotaro; Shibayama, Kentaro; Ito, Joji; Watanabe, Hiroyuki; Yashima, Fumiaki; Watanabe, Yusuke; Naganuma, Toru; Araki, Motoharu; Yamanaka, Futoshi; Shirai, Shinichi; Ueno, Hiroshi; Mizutani, Kazuki; Higashimori, Akira; Takagi, Kensuke; Tada, Norio; Yamamoto, Masanori; Hayashida, Kentaro

doi:10.1002/ccd.28935

Cited by 7 publications

(1 citation statement)

References 22 publications

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“…For repeated hospitalizations, an important finding is that nonagenarians were at higher risk whilst earlier studies on TAVI have described favourable outcomes. 12 , 23 Age is a risk factor for hospitalization 24 and one might argue that, despite more frequent hospitalization, nonagenarians will still benefit from the procedure. A careful patient selection in this age group is needed and a study where hospitalization rates for elderly TAVI patients are compared with rates for patients from the general population would be ideal to gain further knowledge.…”

Section: Discussionmentioning

confidence: 99%

Causes, pattern, predictors, and prognostic implications of new hospitalizations after transcatheter aortic valve implantation: a long-term nationwide observational study

Nilsson

Buccheri

Christersson

et al. 2021

European Heart Journal - Quality of Care and Clinical Outcomes

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Aim The aim of this study was to investigate the pattern, causes and predictors of all new hospitalizations in patients who underwent TAVI. Methods and results The nationwide Swedish TAVI-registry was merged with other mandatory health care registries, which enabled the analysis of all TAVI-procedures, new hospital admissions and death between the years 2008 and 2017. A total of 2821 patients underwent TAVI with a mean of 2.5 hospitalizations during a mean Follow-up of 2.2 years. Hospitalizations were associated with worse prognosis. Heart failure (HF) was the most common cause of hospitalization with 19% having at least one hospitalization due to HF causing 16% of all-cause admissions and 50% of cardiovascular admissions. Male gender, age > 90 years, high Charlson Comorbidity Index, atrial fibrillation, present neurologic disease, severe renal impairment, peripheral vascular disease, New York Heart Association class IV, mild or moderate mean aortic valve gradients and pulmonary hypertension were associated with an increased risk for all-cause hospitalizations or death. For cardiovascular hospitalization or death, the pattern was similar, with the addition of impaired systolic left ventricular function as a predictor. Conclusion Multiple hospitalizations after TAVI are common, and are often caused by HF. Reducing the rate of HF hospitalizations is important to mitigate the burden on the health care system due to new hospitalizations after TAVI.

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Section: Discussionmentioning

confidence: 99%