Clinical outcomes of lower limb peripheral vascular disease after endovascular intervention in patients with diabetes mellitus, critical limb ischemia and chronic kidney disease

Abstract

Aim. To assess the extent of the lower limb arterial calcification and to evaluate the long-term outcomes of percutaneous transluminal balloon angioplasty (PTBA) in patients with diabetes mellitus (DM), critical limb ischemia (CLI) and chronic kidney disease (CKD). Materials and Methods. 94 patients with CLI formed two groups (CKD-positive and CDK-negative). Quantitative assessment of tibial arterial calcification was performed with non-contrast CT. Outcomes of angioplasty were monitored during the 18?6 months of the follow-up period by means of duplex ultrasonography. Results. Long-term outcomes of PTBA were significantly worse in patients with CKD. Nevertheless, limb preservation and survival rates were relatively satisfactory in both groups (74% and 72%, respectively). Conclusion. PTBA in patients with DM, CLI and CKD presents a technical challenge. Despite that, in many cases the endovascular intervention allows avoiding high-level amputations and improves survival rates.

The clinical course of critical limb ischaemia and the role of endovascular revascularisation in patients with diabetes

“…Диффузное ате-р о с к л е р о т и ч е с к о е поражение в сочета-нии с выраженным медиакальцинозом сосудистой стенки наиболее характерно для пациентов с СД и хронической болезнью почек (ХБП) [13]. Тяжесть мор-фологической картины поражений артериального русла у больных СД и ХБП, особенно на лечении программным гемодиализом (рис.…”

“…Развитие реокклюзий целевых сосудов наиболее ха-рактерно для пациентов с СД и терминальной стадией ХБП в течение первого года наблюдения [13].…”