Clinical Outcomes of Infective Endocarditis in Injection Drug Users

Rudasill, Sarah; Sanaiha, Yas; Mardock, Alexandra L.; Khoury, Habib; Xing, Hanning; Antonios, James; McKinnell, James A.; Benharash, Peyman

doi:10.1016/j.jacc.2018.10.082

Cited by 156 publications

(137 citation statements)

References 28 publications

Supporting

Mentioning

113

Contrasting

Unclassified

Order By: Relevance

“…In addition, 50% of the individuals who were discharged AMA were readmitted within 30 days. Prior studies have reported the prevalence of 30‐day readmission ranging from 20% to 30% for patients who are discharged AMA 3 . Our study failed to show any association between MOUD use before or during the hospitalization on 30‐day readmission.…”

Section: Discussioncontrasting

confidence: 85%

“…Prior studies have reported the prevalence of 30-day readmission ranging from 20% to 30% for patients who are discharged AMA. 3 Our study failed to show any association between MOUD use before or during the hospitalization on 30-day readmission. The reason for this may be due to the severity of the individuals' underlying medical issues, and that hospitalizations can be extremely disruptive to their lives, regardless of engagement with MOUD.…”

Section: Discussioncontrasting

confidence: 80%

“…In the context of the growing opioid crisis, increasing numbers of people who inject drugs (PWID) are hospitalized for infective endocarditis 1 . Studies have consistently found that hospitalized PWID are discharged against medical advice (AMA) frequently, with prevalence ranging from 4.8% to 49% 2‐4 . AMA discharges are associated with higher mortality rates, more frequent readmissions, and greater likelihood of future AMA discharges 5 .…”

Section: Introductionmentioning

confidence: 99%

“…1 Studies have consistently found that hospitalized PWID are discharged against medical advice (AMA) frequently, with prevalence ranging from 4.8% to 49%. [2][3][4] AMA discharges are associated with higher mortality rates, more frequent readmissions, and greater likelihood of future AMA discharges. 5 Reasons for the AMA discharge may include the desire to use drugs, opioid withdrawal, poor pain control, poor communication with staff, or feeling stigmatized.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Impact of Medications for Opioid Use Disorder on Discharge Against Medical Advice Among People Who Inject Drugs Hospitalized for Infective Endocarditis

et al. 2020

View full text Add to dashboard Cite

Background and Objectives The impact of medications for opioid use disorder (MOUD) on against medical advice (AMA) discharges among people who inject drugs (PWID) hospitalized for endocarditis is unknown. Methods A retrospective review of all PWID hospitalized for endocarditis at our institution between 2016 and 2018 (n = 84). Results PWID engaged with MOUD at admission, compared with those who were not, were less likely to be discharged AMA but this did not reach statistical significance in adjusted analysis (odds ratio [OR], 0.22; 95% confidence interval [CI], 0.033‐1.41; P = .11). Among out‐of‐treatment individuals, newly initiating MOUD did not lead to significantly fewer AMA discharges (OR, 0.98; 95% CI, 0.26‐3.7; P = .98). Conclusion and Scientific Significance PWID hospitalized for endocarditis are at high risk for discharge AMA but more research is needed to understand the impact of MOUD. (Am J Addict 2020;29:155–159)

show abstract

Section: Discussioncontrasting

confidence: 85%

Section: Discussioncontrasting

confidence: 80%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Impact of Medications for Opioid Use Disorder on Discharge Against Medical Advice Among People Who Inject Drugs Hospitalized for Infective Endocarditis

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Readmission rates for hospitalization for infective endocarditis and IVDA have been rising and are associated with the current opioid epidemic . Historically, treatment for SUDs has been delivered separately from other health services; hence, the attention of medical personnel in the general hospital setting is often focused solely on surgical/medical interventions for the acute, secondary complications of drug abuse, and not on the primary underlying disease of addiction .…”

mentioning

confidence: 99%

“Dread to treat” patients in cardiac surgery: Global strategies for interacting with cardiothoracic patients with substance use disorders

Allespach

Ståhl

2019

J Card Surg

View full text Add to dashboard Cite

Patients with substance use disorders (SUDs) who undergo valve repair or replacement are often readmitted to the hospital after discharge secondary to recidivism. These "dread to treat" patients pose a unique dilemma for cardiac surgeons who often must make the extremely difficult decision of whether to perform a valve replacement in a recidivist patient with SUDs. This editorial focuses on illuminating strategies which surgeons can administer to patients with SUDs to improve quality of care and reduce provider distress. K E Y W O R D S behavioral interventions, intravenous drug abuse, substance use disorders, surgeon wellness, valve repair/replacement Among the most difficult types of surgical patients to treat are those who struggle with substance addiction. Often complicating their hemodynamic and cardiovascular management after cardiac surgery are challenges with pain management and Cardiac Surgical Intensive Care Unit (CSICU)behavior. These issues impact the primary decision of basic management

show abstract

Risk of New Bloodstream Infections and Mortality Among People Who Inject Drugs With Infective Endocarditis

et al. 2020

View full text Add to dashboard Cite

IMPORTANCE People who inject drugs (PWID) who are being treated for infective endocarditis remain at risk of new bloodstream infections (BSIs) due to ongoing intravenous drug use (IVDU). OBJECTIVES To characterize new BSIs in PWID receiving treatment for infective endocarditis, to determine the clinical factors associated with their development, and to determine whether new BSIs and treatment setting are associated with mortality.

show abstract

Clinical Outcomes of Infective Endocarditis in Injection Drug Users

Cited by 156 publications

References 28 publications

Impact of Medications for Opioid Use Disorder on Discharge Against Medical Advice Among People Who Inject Drugs Hospitalized for Infective Endocarditis

Impact of Medications for Opioid Use Disorder on Discharge Against Medical Advice Among People Who Inject Drugs Hospitalized for Infective Endocarditis

“Dread to treat” patients in cardiac surgery: Global strategies for interacting with cardiothoracic patients with substance use disorders

Risk of New Bloodstream Infections and Mortality Among People Who Inject Drugs With Infective Endocarditis

Contact Info

Product

Resources

About