Clinical outcomes of hemiarthroplasty and biological resurfacing in patients aged younger than 50 years

Hammond, Lcdr C.D.R.J.; Lin, Emery C.; Harwood, Daniel; Juhan, Tristan; Gochanour, Eric; Klosterman, Emma L.; Cole, Brian J.; Nicholson, Gregory P.; Verma, Nikhil N.; Romeo, Anthony A.

doi:10.1016/j.jse.2013.04.015

Cited by 34 publications

(47 citation statements)

References 16 publications

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“…The results in the literature have been variable. [27][28][29][30] Poor results could be due to the nature of the disease or to the choice of graft.…”

Section: Biologic Glenoid Resurfacingmentioning

confidence: 99%

Orthopedic Applications of Acellular Human Dermal Allograft for Shoulder and Elbow Surgery

Acevedo

Shore

Mirzayan

2015

Orthopedic Clinics of North America

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“…The results in the literature have been variable. [27][28][29][30] Poor results could be due to the nature of the disease or to the choice of graft.…”

Section: Biologic Glenoid Resurfacingmentioning

confidence: 99%

Orthopedic Applications of Acellular Human Dermal Allograft for Shoulder and Elbow Surgery

Acevedo

Shore

Mirzayan

2015

Orthopedic Clinics of North America

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“…Die sekundä-re Implantation der Glenoidkomponente kann zwar zu einer Verbesserung der klinischen Ergebnisse in Bezug auf die Beschwerdesymptomatik und die Funktionalität führen, allerdings zeigen sich die Ergebnisse der Primärimplantation einer Glenoidkomponente unterlegen. Caroll et al [5] publizierten ihre Ergebnis von 16 Patienten nach sekundärem Glenoideinbau mit einem mittleren Nachuntersuchungszeitraum von 5,5 Jahren. Bei 47 % der Patienten konnten nur unbefriedigende klinische Ergebnisse erzielt werden und ein Drittel der Patienten beklagte eine Schmerzpersistenz.…”

Section: Hemiendoprotheseunclassified

“…Die einzige Arbeit, welche das "biologic resurfacing" mit der HEP vergleicht, stammt von Hammond et al [16]. Sie verglichen in ihrer retrospektiven Untersuchung insgesamt 44 Patienten: 23 Patienten wurden nur mit einer HEP und 21 mit beiden Verfahren operiert.…”

Section: Introductionunclassified

“…Sie verglichen in ihrer retrospektiven Untersuchung insgesamt 44 Patienten: 23 Patienten wurden nur mit einer HEP und 21 mit beiden Verfahren operiert. Alle Patienten waren dabei zum Zeitpunkt der Operation jünger als 50 (16,6) Jahre. Der mittlere Nachuntersuchungszeitraum betrug 3,8 (1,0-7,4) Jahre für die HEP-Gruppe und 3,6 (2,0-5,9) Jahre für die Gruppe mit dem ergänzenden biologischen Glenoidersatz.…”

Section: Introductionunclassified

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Alternative Behandlungsoptionen am Glenoid

2015

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“…41,47 Unfortunately, alternative strategies such as biologic resurfacing procedures (eg, using lateral meniscus or dermal allografts) and glenoid osteochondral grafting result in unacceptably high rates of failure. 22,49 However, bone marrow–stimulating procedures such as microfracture (MFx) 12,36 and concentric reaming of the glenoid 7 have shown promising short-term and midterm results.…”

mentioning

confidence: 99%

Assessment of glenoid chondral healing: comparison of microfracture to autologous matrix-induced chondrogenesis in a novel rabbit shoulder model

Wang

Karas

Lee

et al. 2015

Journal of Shoulder and Elbow Surgery

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Background Management of glenohumeral arthrosis in young patients is a considerable challenge, with a growing need for non-arthroplasty alternatives. The objectives of this study were to develop an animal model to study glenoid cartilage repair and to compare surgical repair strategies to promote glenoid chondral healing. Methods Forty-five rabbits underwent unilateral removal of the entire glenoid articular surface and were divided into 3 groups—duntreated defect (UD), microfracture (MFx), and MFx plus type I/III collagen scaffold (autologous matrix-induced chondrogenesis [AMIC])—for the evaluation of healing at 8 weeks (12 rabbits) and 32 weeks (33 rabbits) after injury. Contralateral shoulders served as unoperated controls. Tissue assessments included 11.7-T magnetic resonance imaging (long-term healing group only), Equilibrium Partitioning of an Ionic Contrast agent via microcomputed tomography (EPIC-μCT), and histologic investigation (grades on International Cartilage Repair Society II scoring system). Results At 8 weeks, x-ray attenuation, thickness, and volume did not differ by treatment group. At 32 weeks, the T2 index (ratio of T2 values of healing to intact glenoids) was significantly lower for the MFx group relative to the AMIC group (P = .01) whereas the T1ρ index was significantly lower for AMIC relative to MFx (P = .01). The micro–computed tomography–derived repair tissue volume was significantly higher for MFx than for UD. Histologic investigation generally suggested inferior healing in the AMIC and UD groups relative to the MFx group, which exhibited improvements in both integration of repair tissue with subchondral bone and tidemark formation over time. Discussion Improvements conferred by AMIC were limited to magnetic resonance imaging outcomes, whereas MFx appeared to promote increased fibrous tissue deposition via micro–computed tomography and more hyaline-like repair histologically. The findings from this novel model suggest that MFx promotes biologic resurfacing of full-thickness glenoid articular injury. Level of evidence Basic Science Study, In Vivo Animal Model.

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Clinical outcomes of hemiarthroplasty and biological resurfacing in patients aged younger than 50 years

Cited by 34 publications

References 16 publications

Orthopedic Applications of Acellular Human Dermal Allograft for Shoulder and Elbow Surgery

Orthopedic Applications of Acellular Human Dermal Allograft for Shoulder and Elbow Surgery

Alternative Behandlungsoptionen am Glenoid

Assessment of glenoid chondral healing: comparison of microfracture to autologous matrix-induced chondrogenesis in a novel rabbit shoulder model

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