Clinical outcomes of elderly patients undergoing chronic peritoneal dialysis: experiences from one center and a review of the literature

Yang, Xiao; Fang, Wei; Kothari, Jatin; Khandelwal, Mukesh; Naimark, David; Jassal, Sarbjit V.; Bargman, Joanne M.; Oreopoulos, Dimitrios G.

doi:10.1007/s11255-007-9279-6

Cited by 36 publications

(33 citation statements)

References 27 publications

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“…[9][10][11][12][13] The result of this study is similar to that of the previous results. The elderly patients on PD present with important morbidity, which often makes it difficult to indicate the start of PD.…”

Section: Discussionsupporting

confidence: 89%

Risk Factors for Mortality in Stable Peritoneal Dialysis Patients

et al. 2012

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Background: The mortality rates of end-stage renal disease patients have significantly declined over the past decade. However, there are few reports on the risk factors for mortality in stable peritoneal dialysis (PD) patients who survive for a considerable time. Patients and methods: We reviewed the medical records and identified all adult patients who received PD between April 2001 and March 2009 in our institution. The total cohort was 550 patients. Among these patients, 383 patients were enrolled as stable PD patients. Results: The cumulative survival of the stable PD patients was 91.6% at 3 years and 78.7% at 5 years. On univariate analysis, old age (≥65 years of age), hypoalbuminemia (<35 g/L), log C-reactive protein (CRP) (≥0.84), phosphorus (<1.13 mmol/L), statin, icodextrin, and the Davies index were associated with mortality for all PD patients. Old age, hypoalbuminemia, log CRP, phosphorus, the residual renal function (RRF) (≤4 mL/min/1.73 m 2 ) at 24 months, renin-angiotensin system blockade, icodextrin, and the Davies index were associated with mortality for the stable PD patients. Multivariate analysis showed that, among the variables, age, log CRP, phosphorus, initial RRF, and the Davies index were associated with mortality for all PD patients. In stable PD patients, age, log CRP, phosphorus, RRF at 24 months, and the Davies index were associated with mortality. Conclusion: Initial high RRF combined with the RRF preservation, maintenance of proper phosphorus, control of inflammation, and proper management of comorbidities may help to improve the survival of PD patients including stable PD patients.

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Section: Discussionsupporting

confidence: 89%

Risk Factors for Mortality in Stable Peritoneal Dialysis Patients

et al. 2012

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“…Regarding the protective effect of older age on technique failure, information in the literature is controversial (29)(30). The greater risk of technique failure in elderly patients could be attributed to reasons such as an inability to perform PD because of cognitive or mechanical reasons; however, similar to the present results Lim et al (25), in a large Australia and New Zealand cohort, reported that compared to younger patients, elderly patients presented a higher risk of peritonitis-related mortality, but a lower risk of technique failure.…”

Section: Discussionmentioning

confidence: 99%

Novel Predictors of Peritonitis-Related Outcomes in the BRAZPD Cohort

Olandoski

Júnior

Martin

et al. 2014

Peritoneal Dialysis International

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“…One study reported equivalent technique survival for all ages at 5 years (52). Peritonitis data are variable (53)(54)(55)(56). Some studies show an increased rate, some a decreased rate, and others the same rate for elderly and younger patients.…”

Section: Choice Of Rrt Hd Versus Peritoneal Dialysismentioning

confidence: 99%

Renal Replacement Therapy in the Elderly Population

Berger¹,

Hedayati

2012

Clinical Journal of the American Society of Nephrology

101

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Summary ESRD has become an important problem for elderly patients. The segment of the ESRD population age 65 years or older has grown considerably, and this growth is expected to accelerate in coming years. Nephrologists caring for the elderly with advanced kidney disease will encounter patients with comorbid conditions common in younger patients, as well as physical, psychological, and social challenges that occur with increased frequency in the aging population. These challenging factors must be addressed to help inform decisions regarding the option to initiate dialysis, the choice of dialysis modality, whether to pursue kidney transplantation, and end-of-life care. This article will highlight some common problems encountered by elderly patients with ESRD and review data on the clinical outcomes of elderly patients treated with different modalities of dialysis, outcomes of kidney transplantation in the elderly, and nondialytic management of CKD stage 5.

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Clinical outcomes of elderly patients undergoing chronic peritoneal dialysis: experiences from one center and a review of the literature

Cited by 36 publications

References 27 publications

Risk Factors for Mortality in Stable Peritoneal Dialysis Patients

Risk Factors for Mortality in Stable Peritoneal Dialysis Patients

Novel Predictors of Peritonitis-Related Outcomes in the BRAZPD Cohort

Renal Replacement Therapy in the Elderly Population

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