Clinical outcomes of diode laser as an adjunct to nonsurgical periodontal therapy for residual periodontal pockets in mandibular second molars—a randomized controlled clinical trial

Lu, Jiawei; Huang, Shihui; Lei, Xinghui; Deng, Li; Luo, Lijun

doi:10.1007/s00784-023-05071-6

Cited by 3 publications

(1 citation statement)

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“…PDLSCs also promote CD-136, IL-10, and Arginase 1, which enhances the anti-inflammatory M2 macrophage phenotypic polarization in addition to inhibiting T cell proliferation (Shin et al, 2017;. These evidences suggest that, to harness the maximum regenerative potential of PDLSCs, it is imperative to maintain the state of controlled inflammation or homeostasis which favors repair which is possible only through the elimination of the pro-inflammatory components, bacteria and endotoxins via mechanical debridement thereby, declaring LASERs to be an adjunct to the mechanical therapy (Jiang et al, 2022;Lu et al, 2023).…”

Section: Periodontal Ligament Stem Cells (Pdlscs)mentioning

confidence: 99%

The effect of adjunctive LASER application on periodontal ligament stem cells

Ponnaiyan,

Rughwani,

Shetty

et al. 2024

Front. Cell Dev. Biol.

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Periodontal regeneration involves the composite action of cell, scaffolds and signaling molecules. There are numerous autologous sources of regenerative cells which are present close to the vicinity of the periodontally debilitated site, the primary one being the periodontal ligament stem cell, which is believed to have a key role in regeneration. Various methods can be harnessed to optimize and enhance the regenerative potential of PDLSCs such as the application of LASERs. In the last few years there have been various studies which have evaluated the effect of different types of LASERs on PDLSCs and the present review summarizes the photo-biomodulative activity of LASERs in general and its beneficial role in the stimulation of PDLSC specifically.

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Section: Periodontal Ligament Stem Cells (Pdlscs)mentioning

confidence: 99%