2011
DOI: 10.1016/j.jacc.2011.03.074
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Clinical Outcomes in Patients Undergoing Percutaneous Closure of Periprosthetic Paravalvular Leaks

Abstract: Percutaneous closure of symptomatic paravalvular leaks, facilitated by integrated imaging modalities has a high rate of acute and long-term success and appears to be effective in managing symptoms of heart failure and hemolytic anemia.

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Cited by 295 publications
(262 citation statements)
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“…Hourihan performed the first reported transcatheter closure of PVL in 1992 with double umbrella device and since then the technique is considerably developed [3]. Percutaneous PVL closure has been shown to be safe and effective treatment in different series [4,[5][6][7].…”
Section: Discussionmentioning
confidence: 99%
“…Hourihan performed the first reported transcatheter closure of PVL in 1992 with double umbrella device and since then the technique is considerably developed [3]. Percutaneous PVL closure has been shown to be safe and effective treatment in different series [4,[5][6][7].…”
Section: Discussionmentioning
confidence: 99%
“…For this reason, when it comes to treating intermediate and low risk patients, the occurrence of "more than mild" PVL should unquestionably be avoided. Transcatheter devices specifically designed to solve PVL after TAVI are not currently available and results after closure with other kind of vascular occluders are suboptimal (22). New generation TAVI devices have already been engineered with specific novel features capable of reducing, but still not eliminating, PVL.…”
Section: Hemodynamic Performancementioning
confidence: 99%
“…1 Yet the presence of a mechanical aortic valve (AV) prosthesis has been considered a contraindication to retrograde percutaneous closure of a mitral paravalvular leak (MPVL). 2,3 In one case of MPVL with a mechanical AV prosthesis, 4 a retrograde approach was attempted but failed, because one of the discs of the prosthesis was repeatedly blocked as the catheter advanced through the AV prosthesis, which led to severe hemodynamic deterioration.…”
Section: Successful Casesmentioning
confidence: 99%