Clinical outcomes in children with adrenal neuroblastoma undergoing open versus laparoscopic adrenalectomy

Kelleher, Cassandra M.; Smithson, Lauren; Nguyen, Louis L.; Casadiego, G P Ibero; Nasr, A.H.; Irwin, Meredith S.; Gerstle, J. Ted

doi:10.1016/j.jpedsurg.2013.03.056

Cited by 62 publications

(29 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Only one series compared laparoscopy and open approach for adrenal neuroblastomas smaller than five cm, without vascular encasement and irrespective of risk group categorization. The authors concluded in favor of laparoscopy despite the small number of patients in each group . Further, no other abdominal locations were reported on the contrary of our report.…”

Section: Discussioncontrasting

confidence: 80%

Minimally invasive surgery of neuroblastic tumors in children: Indications depend on anatomical location and image‐defined risk factors

Irtan

Brisse

Minard‐Colin

et al. 2014

Pediatric Blood & Cancer

View full text Add to dashboard Cite

show abstract

Section: Discussioncontrasting

confidence: 80%

Minimally invasive surgery of neuroblastic tumors in children: Indications depend on anatomical location and image‐defined risk factors

Irtan

Brisse

Minard‐Colin

et al. 2014

Pediatric Blood & Cancer

View full text Add to dashboard Cite

show abstract

“…Kelleher et al compared the clinical outcomes between laparotomy and laparoscopy, including advanced cases and found no difference in mortality among patients who met the selection criteria for the laparoscopic resection which were absence of vascular encasement and size <5 cm as the greatest dimension. Other patients underwent laparotomy [19, 23]. …”

Section: Discussionmentioning

confidence: 99%

Laparoscopic resection of neuroblastomas in low- to high-risk patients without image-defined risk factors is safe and feasible

et al. 2017

View full text Add to dashboard Cite

BackgroundSeveral studies have reported that minimally invasive surgery (MIS) might be considered for resecting neuroblastomas without image-defined risk factors (IDRFs); however, there are no studies comparing the outcomes of laparotomy and laparoscopy in IDRF-negative patients. Thus, we investigated the feasibility of laparoscopic surgery and compared the two abovementioned approaches.MethodsTo compare the effects of laparotomy with those of laparoscopy in patients with neuroblastomas without IDRFs, the following items were retrospectively compared: largest tumor dimension, volume of blood loss, time required to initiate postoperative feeding, locoregional recurrence rate, survival, etc.ResultsNine patients without IDRFs (three at low-to-medium risk and six at high risk) underwent laparotomy, and seven patients without IDRFs (two at low-to-medium risk and five at high risk) underwent laparoscopy. Median duration of surgery was 221 (130–304) and 172 (122–253) min in the laparotomy and laparoscopy groups, respectively, showing no significant difference. Median postoperative time required for resuming meal consumption was significantly longer in the laparotomy (4 days; 2–5) group than that in the laparoscopy group (3 days; 2–3; p = 0.023). Median blood loss was significantly higher in the laparotomy group (5 ml/Kg;2.6–16) than that in the laparoscopy group (2.1 ml/Kg;0.1–4.0; P = 0.037). Median follow-up period was 81 (52–94) and 21 (17–28) months, locoregional recurrence rates were 22 and 0% at 1 year, 1-year progression-free survival rates were 78 and 100%, and overall survival rates were 67 and 100% in the laparotomy and laparoscopy groups, respectively, with no significant differences.ConclusionsMIS for the treatment of neuroblastomas without IDRFs in low- to high-risk patients is safe and feasible and does not compromise the treatment outcome.

show abstract

“…In addition, some studies have compared the laparoscopic and open procedures and observed that the time to resumption of diet, the time to return of bowel function, and the length of hospital stay were shorter in the laparoscopic group, allowing postoperative chemotherapy to be started at the earliest time. 12,25 Additional advantages demonstrated were a lower morbidity rate, easier pain control, greater mobility after surgery, and notably better cosmetic results. 11,12,19,20,26 Although all data reported suggest that laparoscopy could potentially offer great short-term benefits in the pediatric population, there are still doubts about the use of laparoscopic adrenalectomy for malignant tumors in terms of tumoral spillage and port-site disease recurrence.…”

Section: Discussionmentioning

confidence: 99%

Transperitoneal Laparoscopic Adrenalectomy in Children

GelminiRoberta¹,

Luca²,

CatellaniBarbara³

et al. 2015

Journal of Laparoendoscopic & Advanced Surgical Techniques

View full text Add to dashboard Cite

Purpose: The use of a minimally invasive approach for adrenalectomy is poorly defined in pediatric patients, although laparoscopic adrenalectomy is considered a standard procedure in adults. The aim of our study was to describe the safety and feasibility of minimally invasive adrenalectomy in children on the basis of surgical skills and results. Materials and Methods:This was a retrospective study of 4 pediatric laparoscopic adrenalectomies performed at our center between 2009 and 2012. All patients underwent transperitoneal lateral laparoscopic adrenalectomies (2 right and 2 left adrenalectomies).Results: Four laparoscopic adrenalectomies were performed. Indications for surgery were neuroblastoma in 2 patients, secernent adrenocortical tumor in 1 patient, and adrenocortical nodular hyperplasia in 1 patient. Patients had a mean age of 87 months (range, 17-156 months) at diagnosis, and the average lesion size was 3.23 cm (range, 0.7-6.4 cm). All laparoscopic adrenalectomies were successful, no conversions to open surgery were required, and no postoperative complications or deaths occurred. The average operating time was 105 minutes (range, 80 -130 minutes), blood loss during surgery was minimal, and the mean postoperative hospital stay was 3.75 days (range, 3-5 days). None of the patients showed signs of recurring disease at 15-month follow-up. Conclusions:Laparoscopic adrenalectomy is a safe, feasible, and reproducible technique offering numerous advantages, including shortening of operating times and postoperative hospital stays, as well as reduction of blood loss and complications. It also provides good visibility and easy access to other organs.

show abstract

Clinical outcomes in children with adrenal neuroblastoma undergoing open versus laparoscopic adrenalectomy

Cited by 62 publications

References 18 publications

Minimally invasive surgery of neuroblastic tumors in children: Indications depend on anatomical location and image‐defined risk factors

Minimally invasive surgery of neuroblastic tumors in children: Indications depend on anatomical location and image‐defined risk factors

Laparoscopic resection of neuroblastomas in low- to high-risk patients without image-defined risk factors is safe and feasible

Transperitoneal Laparoscopic Adrenalectomy in Children

Contact Info

Product

Resources

About