Clinical Outcomes and Global Health After Joint Debridement in Adult-Onset Septic Arthritis: A Prospective Observational Study

Malipeddi, Ranjith; Nema, Sandeep Kumar; Gopisankar, B; Prabu, M.; Pasupathy, P.; Gandhi, B. Suresh

doi:10.1007/s43465-021-00389-3

Cited by 2 publications

(2 citation statements)

References 21 publications

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“…In our study, it was revealed that the clinical results were similar to these studies and Some studies also claim that the effect of bacterial isolation on the outcome of septic arthritis is low. [11] Even if CN is present, the treatment process can be provided without any problems with empirical antibiotics.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Culture-Negative Adult Knee Septic Arthritis Patients with Culture-Positive Patients

Hançerli

2024

Comprehensive Med

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Objective: This study aimed to clinically compare patients with culture-negative (CN) adult knee septic arthritis and culture-positive (CP) adult knee septic arthritis patients.Materials and Methods: 51 patients who were operated on with the diagnosis of adult knee septic arthritis between June 2016 and May 2023 were retrospectively examined. While 23 patients with CN were called Group 1, 28 patients with CP were called Group 2. Age, gender, side, C-reactive protein (Crp) value at admission, culture results, hospital stay and follow-up periods were evaluated. In clinical evaluation, knee ROM (range of motion) and visual analog score (VAS) were evaluated.Results: Both groups had similar distributions in terms of age, gender, side and follow-up periods. Group 1's Crp level at admission and total hospital stay were lower than Group 2. (p=0.018/p=0.0001) ROM and VAS scores of both groups were similar. No patient developed deep infection. Conclusion:In CN adult knee septic arthritis patients, the average Crp values at the time of admission are lower and the hospital stay is shorter. Clinically, they have similar results to CP patients in terms of ROM and VAS.

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Section: Discussionmentioning

confidence: 99%

Comparison of Culture-Negative Adult Knee Septic Arthritis Patients with Culture-Positive Patients

Hançerli

2024

Comprehensive Med

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“…24,28 However, more recent studies dispute this, with no difference in outcome (mortality, morbidity, functional outcome and quality of life) with at least a 4-day delay in presentation post-onset of symptoms or a delay of 42 hours between clinical diagnosis and arthroscopic joint lavage. 5,29,30 Clearly, larger studies focussing on SACA are needed to assess how many SACA patients are being misdiagnosed initially and what the outcome burden is for these patients who have a delay of up to 48 hours until a positive sample culture proves the joint infection.…”

Section: Discussionmentioning

confidence: 99%

Concomitant septic and crystal arthropathy: a single-centre 10-year retrospective observational study in New Zealand

Mukerji,

Ryan,

Simmonds

et al. 2024

NZMJ

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aim: To quantify and characterise patients with coexistent septic arthritis (SA) and crystal arthritis (CA) (SACA) in an emergency department (ED) setting. methods: A single-centre, retrospective, 10-year observational study was conducted at a major referral centre. Patients with a positive joint aspirate for CA or SA carried out in ED, were included. The Newman criteria were utilised to define SA. results: Of the 567 patients included in the final analysis, 427 had CA and 140 had a final diagnosis of SA. Twenty-three point six percent of patients diagnosed with SA had concomitant CA, while 7.2% of patients diagnosed with CA had concomitant SA. The greatest predisposing factors for SACA were previous history of gout, rheumatoid arthritis, being immunocompromised or having joint metalware. Synovial fluid (SF) white cell count (WCC) showed excellent predictive capability for joint infection with the area under the receiver operating characteristic curves (AUROCs) of 0.81 and 0.87 for SA and SACA respectively. The receiver operating characteristic curves (ROCs) reported a SF WCC cutoff of 32,000/mm3 allowed for 100% sensitivity and approximately 50% specificity. conclusions: SACA remains a small but important sub-group of patients at risk of misdiagnosis of CA alone. SF WCC of 32,000/mm3 may be a better cutoff than the traditionally accepted 50,000/mm3, possibly warranting inpatient admission for investigation and management of presumed SA.

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Clinical Outcomes and Global Health After Joint Debridement in Adult-Onset Septic Arthritis: A Prospective Observational Study

Cited by 2 publications

References 21 publications

Comparison of Culture-Negative Adult Knee Septic Arthritis Patients with Culture-Positive Patients

Comparison of Culture-Negative Adult Knee Septic Arthritis Patients with Culture-Positive Patients

Concomitant septic and crystal arthropathy: a single-centre 10-year retrospective observational study in New Zealand

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