Clinical outcomes and considerations of gender‐affirming care for transgender and gender‐diverse pediatric and young adult patients with cancer

Kempf, Abigail; Burns, Zackory T.; Guss, Carly E.; Millington, Kate; Pilcher, Sarah; Boyle, Patrick J.; Charlton, Brittany M.; Haas‐Kogan, Daphne A.; Liu, Kevin X.

doi:10.1002/pbc.29851

Cited by 4 publications

(4 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A study revealed that after cancer patients disclosed their name and gender to HCP, 50% of HCP in this cohort continued addressing patients with incorrect pronouns and 28% used the incorrect name in their notes [17]. In addition, 55% of HCP in this study did not note discussing fertility goals of the patient before beginning hormone therapy [17]. Recent reviews confirm that TGD patients often face gender-biased assumptions during their care.…”

Section: Resultsmentioning

confidence: 94%

“…Transgender and gender diverse (TGD) cancer patients face their own unique challenges as HCPs struggle to incorporate gender affirming care [16 ▪▪ ,17,18]. A study revealed that after cancer patients disclosed their name and gender to HCP, 50% of HCP in this cohort continued addressing patients with incorrect pronouns and 28% used the incorrect name in their notes [17]. In addition, 55% of HCP in this study did not note discussing fertility goals of the patient before beginning hormone therapy [17].…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Sexual and gender diversity in cancer care and survivorship

Schulz-Quach

Kennedy

Lyver

2023

Current Opinion in Supportive &Amp; Palliative Care

View full text Add to dashboard Cite

Purpose of the review Sexual and gender diverse (SGD) cancer patients possess unique identities and needs that must be considered during their cancer care. This narrative review explores the current literature on sexual and gender diversity in cancer care and survivorship, in addition to providing recommendations encouraged by the current literature. Recent findings We performed a literature search for articles published in English between January 2021 and June 2022 in Medline ALL and Embase. Fifty-two studies were included in this review. The many identities encapsulated in 2SLGBTQIA+ (2 Spirited, Lesbian, Gay, Bisexual, Transgender, Queer, Intersexual, Asexual, Agender, Aromantic and all gender identities and sexual orientations that are not listed) communities each have their own unique backgrounds, needs and disparities in cancer care and survivorship. However, we also identified specific protective factors in the cancer experience of SGD patients such as reports of higher resiliency and stronger support networks. Much of the recent research features recommendations on improving cancer care by creating inclusive patient questionnaires, improving in-person and online resources, and educating healthcare providers and patient-facing staff on inclusive care. Summary SGD patients have their own specific challenges during and following their cancer care. As the research continues to grow, we gain a better understanding of the needs of these patients and future steps to take to improve SGD patients’ cancer experience.

show abstract

Section: Resultsmentioning

confidence: 94%

Section: Resultsmentioning

confidence: 99%

Sexual and gender diversity in cancer care and survivorship

Schulz-Quach

Kennedy

Lyver

2023

Current Opinion in Supportive &Amp; Palliative Care

View full text Add to dashboard Cite

show abstract

“…This retrospective cohort of transgender and gender-expansive people with cancer treated at three institutions was identified, as previously reported, using keyword searches of each institution’s medical record and treatment planning system ( 14 , 15 ). All three institutions currently have affiliated transgender health centers.…”

Section: Methodsmentioning

confidence: 99%

“…A qualitative study of radiology and radiation oncology clinicians identified major gaps in training, knowledge, and confidence in caring for transgender people ( 13 ). Prior studies have reported outcomes of cancer treatment in cohorts of transgender patients ( 14 , 15 ), but none have investigated the impact of radiation therapy (RT) on gender-affirming care.…”

Section: Introductionmentioning

confidence: 99%

Clinical outcomes of radiation therapy for transgender and gender-expansive people with cancer

Mansur,

Kempf,

Bitterman

et al. 2023

Front. Oncol.

Self Cite

View full text Add to dashboard Cite

IntroductionApproximately 1.6 million people in the US identify as transgender, many of whom undergo gender-affirming medical or surgical therapies. While transgender individuals are diagnosed with cancer at similar rates as those who are cisgender, the impacts of radiation therapy on outcomes of gender-affirming care in transgender, nonbinary, and gender-expansive people with cancer are understudied. We report on the experiences and outcomes of transgender and gender-expansive patients receiving radiation therapy for cancer treatment.MethodsThis study is a multi-institutional retrospective review of patients evaluated from 2005-2019 identified as transgender or gender-expansive in the medical record and treated with radiation therapy.ResultsWe identified 23 patients who received radiation to 32 sites, including 12 (38%) to the brain, head, or neck, 8 (25%) to the thorax, and 7 (22%) to the pelvis. Seventeen patients (74%) received gender-affirming hormone therapy and 13 patients (57%) underwent gender-affirming surgery. Four patients had pelvic radiation before or after gender-affirming pelvic surgery, including two trans women who had pelvic radiation after vaginoplasty. Four patients had radiation to the chest or thorax and gender-affirming chest or breast surgery, including two trans men with breast cancer. Two pediatric patients developed hypopituitarism and hypogonadism secondary to radiation therapy and, as adults, changed their hormone replacement therapy to affirm their transgender identities.DiscussionTransgender people with cancer undergo radiation therapy for a wide range of cancers. Understanding their prior gender-affirming medical or surgical treatments and future gender affirmation goals may identify important considerations for their oncologic care.

show abstract