Clinical outcome in 287 consecutive young adults (15 to 45 years) with ischemic stroke

Leys, Didier; Bandu, L.; Hénon, Hilde; Lucas, Christian; Mounier‐Véhier, F.; Rondepierre, Ph.; Godefroy, Olivier

doi:10.1212/wnl.59.1.26

Cited by 338 publications

(317 citation statements)

References 44 publications

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“…Our results did not confirm the favourable prognosis in young patients in other studies. [20][21][22] The percentage of recurrence was remarkably high, both in patients with and without therapy change, 33 and 14% respectively. However, the two patients with recurrence and a change in therapy had risk factors for atherosclerosis, i.e.…”

Section: Therapeutic Consequences Of Echocardiograph Findingsmentioning

confidence: 99%

Influence of transoesophageal echocardiography on therapy and prognosis in young patients with TIA or ischaemic stroke

Rettig¹,

Bouma²,

Brink³

2009

NHJL

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Objective. To determine the influence of transoesophageal echocardiography (TEE) on therapy and prognosis in patients with cryptogenic transient ischaemic attack (TIA) or ischaemic stroke under the age of 50 years. Methods and results. We evaluated all patients aged 50 and under who were referred to our university hospital for cryptogenic TIA or ischaemic stroke during the period 1 January 1996 to 31 December 2004. All patients underwent both transthoracic echocardiography (TTE) and TEE. Patients with known pre-existent heart disease, such as atrial fibrillation, were excluded. Eighty-three patients with TIA (22) and ischaemic stroke (61) were enrolled. Mean age was 39±8 years (range 18 to 50). In 30% of the patients TEE detected one or more potential cardioembolic source, compared with 10% for TTE (p=0.003). Standard treatment (aspirin 38 mg daily) was changed in 7% of the patients due to the TEE findings. Complete followup was obtained in 93% with an average of 5±3 years. Twelve recurrences occurred; two out of six patients (33%) with therapy change and ten out of 71 (14%) of the patients without therapy change had a recurrent TIA or ischaemic stroke. Conclusion. In patients with cryptogenic TIA or ischaemic stroke, TEE is superior to TTE in the detection of a potential cardiac source of embolism.

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Section: Therapeutic Consequences Of Echocardiograph Findingsmentioning

confidence: 99%

Influence of transoesophageal echocardiography on therapy and prognosis in young patients with TIA or ischaemic stroke

Rettig¹,

Bouma²,

Brink³

2009

NHJL

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show abstract

“…Spontaneous cervical artery dissection (sCAD) is a wellrecognized cause of stroke, especially in young patients, with a wide spectrum of clinical presentations [1,2]. Patients may present with isolated local manifestations, ischemic signs or both [3].…”

Section: Introductionmentioning

confidence: 99%

Quality of life in survivors after cervical artery dissection

et al. 2009

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“…Most of the investigations in long-term prognosis have described good functional recovery in young adults with ischemic stroke, since most patients are independent and at least 50% return to work [8][9][10][11][12]. Moreover, some predictive factors for mortality, recurrence, and good/poor functional recovery have been identified [12].…”

Section: Introductionmentioning

confidence: 99%

Long-term prognosis of ischemic stroke in young adults

et al. 2004

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There is limited information about long-term prognosis of ischemic stroke in young adults. Giving the potentially negative impact in physical, social, and emotional aspects of an ischemic stroke in young people, providing early accurate long-term prognostic information is very important in this clinical setting. Moreover, detection of factors associated with bad outcomes (death, recurrence, moderate-to-severe disability) help physicians in optimizing secondary prevention strategies. The present paper reviews the most relevant published information concerning long-term prognosis and predictors of unfavorable outcomes of ischemic stroke affecting young adults. As a summary, we can conclude that, in the long term, stroke in the young adult increases slightly the risk of mortality, implies higher risk of future cardiovascular events, and determines functional limitations in a significant percentage of patients. Nevertheless, in every individual case the prognosis has to be considered depending on several factors (stroke subtype, initial severity, cardiovascular risk factors) that determine the long-term outcomes.

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Clinical outcome in 287 consecutive young adults (15 to 45 years) with ischemic stroke

Abstract: Although young patients who experience ischemic strokes have a low risk of stroke recurrence and myocardial infarction, some patients do not regain independence.

Cited by 338 publications

References 44 publications

Influence of transoesophageal echocardiography on therapy and prognosis in young patients with TIA or ischaemic stroke

Influence of transoesophageal echocardiography on therapy and prognosis in young patients with TIA or ischaemic stroke

Quality of life in survivors after cervical artery dissection

Long-term prognosis of ischemic stroke in young adults

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