Clinical observation of Danhong Injection (herbal TCM product from Radix Salviae miltiorrhizae and Flos Carthami tinctorii) in the treatment of traumatic intracranial hematoma

Protective effect of Danhong injection on cerebral ischemia–reperfusion injury in rats

“…It has been used in a variety of diseases, especially acutely cerebral infarction due to its traditional Chinese medical effects of activating blood circulation and dissipating blood stasis, dredging meridians and collaterals (Tai et al, 2005). Numerous clinical observations have confirmed that stroke patients receiving DH therapy got a favorable outcome Li, 2011;Sun et al, 2009;Zhu and Cui, 2010). However, the underlying therapeutic mechanisms of DH on stroke are still unclear even though it has become the best-selling traditional Chinese medicinal injection currently.…”

Danhong injection attenuates cardiac injury induced by ischemic and reperfused neuronal cells through regulating arginine vasopressin expression and secretion

“…Danhong injection (DHI), made from danshen (Radix Salviae Miltiorrhizae) and honghua (Safflower, Flos Carthami), has been widely used for the prevention and treatment of cardio-cerebrovascular diseases in clinics (Ma et al, 2010;Sun et al, 2009;Yao et al, 2011). Previously, a number of studies showed that the DHI can prevent coronary heart disease through anti-atherosclerotic action, antioxidant activity, reducing the release of creatine kinase (CK) and lactate dehydrogenase (LDH), and prevent the neuronal cells damage by increasing Survivin expression, inhibiting Caspase-3 expression, and increasing GM130 expression (Su et al, 2013).…”

A preliminary evaluation of the effects of Camellia sinensis on stroke induced rat model

“…Kuang et al demonstrated that RSM reduced the lipid peroxidation and afforded cerebral protection against reperfusion injury (Kuang et al, 1996). Recently, it has been shown that RSM has the actions of improving blood circulation and resolving stasis to promote regeneration in traumatic intracranial haematoma (Sun et al, 2009) and also has been used for the m a n a g e m e n t o f c a rd i o v a s c u l a r d i s e a s e ( O ' B r i e n e t a l . , 2 0 1 1 ) .…”