Clinical Method of Photographing the Smaller Blood Vessels and the Circulating Blood in the Bulbar Conjunctiva of Human Subjects

Abstract

During a long-term study of the vascular disease of the smaller blood vessels in diabetes mellitus, the conjunctival vessels in more than 1200 diabetic and nondiabetic subjects have been examined.As part of the ideal delineation of these vessels it was found essential to develop a technic to produce highly magnified, wide-field photographs of the smaller blood vessels and of the circulating blood in human subjects. This

Preliminary Observations on Subjects with Prediabetes

“…Knisley and Bloch's 9 methods for the study of microcirculation, modified by Ditzel, 10 have recently been improved in our laboratory, 11 employing a special Leitz camera. The venule-arteriole ratio in healthy, young subjects without vascular changes was approximately 2:1.…”

Increased Blood Cell Agglutination Following Inges Tion of Fat, a Factor Contributing To Cardiac Is Chemia, Coronary Insufficiency, and Anginal Pain1

“…Photographs taken at various magnifications on the bulbar conjunctiva by Ditzel and St. Clair (27), Marmont, de Matteis and Mariotti (28), Lee and Holze (22), and Bruzelius and Holm (29a) show some of the phenomena which can be routinely observed by this method.…”

“…The method permits observations of (a) a statistically valid sample of the patient's circulating arterial blood (16), (b) what may happen to the statistically valid sample as it passes into or through a peripheral vascular bed, and (c) the conditions of the bulbar conjunctival vessels, either normal or exhibiting the responses to injury delineated by Clark and Clark (17) and confirmed and extended by Brooks, Dragstedt, Warner, and Knisely (18). Variations of this method have been used by other investigators (3,(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29).…”

Zum gegenw�rtigen stand der fr�herkennung des diabetes mellitus

“…Un metodo, al quale spetterä probabilmente maggiore importanza in futuro, è la determinazione del rapporto venule-arteriole nella congiuntiva bulbare mediante uno speciale sistema ottico (5,22,36). Un metodo, al quale spetterä probabilmente maggiore importanza in futuro, è la determinazione del rapporto venule-arteriole nella congiuntiva bulbare mediante uno speciale sistema ottico (5,22,36).…”