Clinical Manifestations of Precocious Puberty and Associated Heritable Diseases: A Case Report

Abstract

The incidence of sexual precocity is 1:10,000, yet previous puberty is infrequently reported. We report a unique case of a young child presenting to the Dermatology clinic for management of acne vulgaris and precocious puberty prompting further work-up to evaluate for McCune Albright Syndrome. While primarily idiopathic, we discuss the associated dermatologic conditions that should be considered in the differential diagnosis, including partial congenital adnexal hyperplasia, Carney Complex, Cushing Syndrome and others when presented with a patient with precocious puberty.