Clinical manifestations of chikungunya infection in the pediatric population: systematic review

Abstract

Objective: To describe the clinical manifestations, especially those related to rheumatology, in the infant and neonatal population with Chikungunya viral, which are described in case studies in the literature. Methods: This is about a systematic review study, conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyzes (PRISMA) methodology. In order to identify the articles about the subject, the databases indexed to the BVS and SCIELO were searched, from June to July 2019, with the following search strategy: chikungunya virus and arthritis, arthralgia rheumatoid and chikungynya fever and arboviruses and arthralgia. Filters used included articles in English that have been published in the last 5 years. Manual searches were made in the bibliographic references of the articles found. Results: Six articles were reviewed, which addressed cases of Chikungunya confirmed pediatric patients. It was noticed that the main clinical manifestations were: fever, cutaneous symptoms, irritability and vomiting. Regarding rheumatologic symptoms, it was concluded that arthralgia and arthritis are uncommon in these patients, and residual arthritis is much less frequent in this age group. Conclusion: The control of the symptomatology and the dissemination of information related to the transmission of the virus helps in the promotion of health, and the complications of the disease must be known in time to be minimized.