Clinical manifestations of acrodermatitis chronica atrophicans in 50 Swedish patients

Asymmetric red-bluish foot due to acrodermatitis chronica atrophicans

“…Namely, ACA can occur up to 8 years after a bite by the tick-borne spirochete Borrelia burgdorferi . Also, 30% of patients with ACA could not recall a tick bite and only 18% had a history of untreated erythema chronicum migrans prior to their symptoms 2. This makes it difficult to connect the dots, as ACA is not often considered in the differential diagnosis of a non-acute red-bluish discoloured extremity.…”

Clinical Manifestations and Treatment of Lyme Disease

“…13 Chronic skin lesions of achrodermatitis chronica can be seen in Asia and Europe with B afzelii infection. 14,15 This condition begins with mild inflammatory lesions of the extensor surfaces of the limbs, which progress to more violaceous lesions that eventually lead to skin atrophy (Fig. 5).…”

A STING from a Tick : Epidemiology, Ecology and Clinical Aspects of Lyme Borreliosis

“…In some patients, sclerotic lesions develop, and peripheral nerves and joints are often affected. ACA is a rare manifestation and is more often diagnosed in women than in men, and the patients are usually older than 40 years (Asbrink et al, 1986;Asbrink & Hovmark, 1988). Patients with ACA usually have a positive serology and pathohistological examinations often reveal lymphocyte and plasma-cell infiltration (Asbrink et al, 1986;Asbrink & Hovmark, 1988).…”