Clinical Manifestations, Diagnostic Assessment, and Etiology of Heart Failure in Older Adults

Ahmed, Ali

doi:10.1016/j.cger.2006.08.002

Cited by 16 publications

(12 citation statements)

References 77 publications

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“…The associated risk factors for developing HF can influence mortality and morbidity, and contribute to the differences in clinical outcomes between genders [3],[4]. For instance, myocardial infarction (MI) as an etiologic factor for HF is detrimental for both genders.…”

Section: Introductionmentioning

confidence: 99%

Gender differences in the etiology of heart failure: A systematic review

Azad

Kathiravelu²,

Minoosepeher³

et al. 2011

Journal of Geriatric Cardiology

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BackgroundHeart failure (HF) is an increasing problem for the aging population, specifically among women. The etiology of HF influences both the selection and outcome of the treatment. There are variations between genders in morbidity and mortality in different studies, possibly reflecting etiology. The objective of this study was to examine the strength of evidence available for gender differences in the etiology of chronic heart failure.MethodsComputer-assisted searches from 1980–2009 for gender differences in the etiology of heart failure were performed (Medline, EMBASE and PubMed). From 2347 abstracts reviewed based on inclusion criteria, 35 original articles were chosen for review. Data extraction was based on observational studies (prospective/retrospective cohort or cross sectional) with a mean follow up of 3 months. There was no interrater variability between the 2 reviewers on data-extraction.ResultsVentricular systolic dysfunction being more associated with male sex, but female sex was more reported to be associated with preserved left ventricular function. Ischemic etiology and associated coronary heart disease were strongly correlated with male sex. The risk for HF was dramatically more elevated for women with systolic hypertension but the association for diabetes mellitus as the etiology of HF was somewhat equal between males and females.ConclusionsOne of the limitations in reaching conclusions about gender differences in cardiovascular disease is that many major clinical trials do not include a gender analysis nor they are powered to do so as women are under-represented in most of the HF studies. The need remains for a well designed prospective study of sufficient numbers of male and female patients with and without heart failure and analyzing etiology and risk factors based on the sex differences.

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Section: Introductionmentioning

confidence: 99%

Gender differences in the etiology of heart failure: A systematic review

Azad

Kathiravelu²,

Minoosepeher³

et al. 2011

Journal of Geriatric Cardiology

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“…About 75% of all people with HF are 65 years of age or older. Women account for half the cases due to their longer life expectancy [5]. Lifetime risk estimates for HF double in people with hypertension, with no gender differences observed [6].…”

Section: Significance Of Heart Failurementioning

confidence: 99%

Relationship Between Heart Failure and Overactive Bladder

Palmer

Busby‐Whitehead

2010

Curr Bladder Dysfunct Rep

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The prevalence of heart failure and overactive bladder, both of which are already quite common, will continue to increase as the population ages. Both create caregiver and self-management burdens, but additional research is needed to understand the burden overactive bladder creates for heart failure patients and their caregivers. Emerging evidence suggests a relationship between heart failure and overactive bladder in which they share a common pathophysiologic pathway via the parasympathetic system. The authors conducted a systematic literature review of overactive bladder in heart failure patients from 2007 to the present. Conflicting evidence exists for the role diuretics play in the prevalence of overactive bladder. Further research is needed to better understand the role of heart failure disease trajectory and its medical management in the natural history of overactive bladder.

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“…When typical symptoms of HF are present, the clinical diagnosis of HF can easily be made. In this situation, a normal systolic LV function would not question the diagnosis but instead classify HF as diastolic HF [28].…”

mentioning

confidence: 99%

Heart Failure in the Elderly

2008

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Heart failure is a progressive and often fatal disorder. The prevalence and incidence of heart failure increase continuously with advancing age. Heart failure imposes an enormous burden on society and healthcare systems as well as on the affected patient and their family. Despite recent major advancements in the pharmacological therapy of heart failure, prognosis remains poor with high morbidity and mortality. With a further aging population, an epidemic-like increase in the number of patients with heart failure is expected, making a holistic approach and the stringent use of currently available diagnostic and therapeutic modalities indispensable. This article summarizes current approaches to the diagnosis as well as to the pharmacological and nonpharmacological therapy of heart failure in the elderly patient.

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Clinical Manifestations, Diagnostic Assessment, and Etiology of Heart Failure in Older Adults

Cited by 16 publications

References 77 publications

Gender differences in the etiology of heart failure: A systematic review

Gender differences in the etiology of heart failure: A systematic review

Relationship Between Heart Failure and Overactive Bladder

Heart Failure in the Elderly

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