Clinical Manifestation, Dermoscopy, and Scanning Electron Microscopy in Two Cases of Contagious Ecthyma (Orf Nodule)

Rezende, Ana Laura Rosifini Alves; Filho, Fred Bernardes; Paula, Natália Aparecida de; Towersey, Loan; Hay, Roderick J.; Frade, Marco Andrey Cipriani

doi:10.1155/2018/2094086

Cited by 6 publications

(8 citation statements)

References 7 publications

(10 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Other reports showed similar features, though further findings were also described in single instances, i.e., hairpin and arborizing vessels, milky-red globules and lacunae, and linearly arranged multiple red–pink clods with surrounding white network [ 103 – 106 ].…”

Section: Resultsmentioning

confidence: 66%

See 1 more Smart Citation

Dermoscopy of Bacterial, Viral, and Fungal Skin Infections: A Systematic Review of the Literature

Chauhan

Meena

Errichetti

2022

Dermatol Ther (Heidelb)

View full text Add to dashboard Cite

Over the last three decades, the use of dermoscopy has been extended to inflammatory and infectious dermatoses. Regarding the latter, while the first applications concerned skin parasitoses, there has been a significant increase in the publication trend regarding nonparasitic dermatoses over recent years, yet data on this topic are sparse and often lack a standardized analytical approach. This systematic literature review summarizes published data on dermoscopy of bacterial, viral, and fungal dermatoses (dermoscopic findings, used setting, pathological correlation, and level of evidence of studies) and provides a homogeneous terminology of reported dermoscopic features according to a standardized methodology. A total of 152 papers addressing 43 different dermatoses and describing 184 different dermoscopic findings were included in the analysis. The majority of them displayed a level of evidence of V (107 single case reports and 40 case series), with only 5 studies showing a level of evidence of IV (case–control studies). Moreover, our analysis also underlined a high variability in the terminology used in published articles (even for the same dermatosis). Therefore, despite significant potential, future studies designed according to a systematic and standardized approach are required for a better characterization of dermoscopy of nonparasitic skin infections. Supplementary Information The online version contains supplementary material available at 10.1007/s13555-022-00855-2.

show abstract

Section: Resultsmentioning

confidence: 66%

“…Ecthyma contagiosum (orf) is a zoonotic disease caused by a DNA parapoxvirus usually transmitted to humans from infected goat and sheep, and presenting on the hands, fingers, feet, legs, and face as single or multiple papules/nodules that ulcerate and then crust [ 102 , 103 ].…”

Section: Resultsmentioning

confidence: 99%

Dermoscopy of Bacterial, Viral, and Fungal Skin Infections: A Systematic Review of the Literature

Chauhan

Meena

Errichetti

2022

Dermatol Ther (Heidelb)

View full text Add to dashboard Cite

show abstract

“…Our dermoscopic findings with white streaks and linear red-pink clods are similar to those reported in the literature. 4,5 In conclusion, we report a case of orf transmitted from camels. Dermoscopically, linear red-pink clods appear to be a useful feature in the diagnosis of orf.…”

mentioning

confidence: 72%

The challenges of teaching and examining dermatology in the medical school curriculum

Gandhi

Arora

2021

Int J Dermatology

View full text Add to dashboard Cite

Orf is usually transmitted to humans through direct contact with infected sheep, goats, or reindeer. Although there are multiple reports of camels infected with orf, 2,3 there is no reported case of transmission to humans. Camel contagious ecthyma (CCE), a highly infectious viral disease of camels caused by a PPV, has been reported in many countries, such as Saudi Arabia, Bahrain, Iran, Sudan, and Nigeria. PPV belongs to the subfamily chordopoxvirinae of the family poxviridae. A well-known member of the genus PPV is the Orf virus (ORFV), which is responsible for the infection of sheep and goats; pseudocowpox virus (PCPV) that infects cattle; and camel PPV (CPPV), which causes CCE. However, CPPV is temporarily classified as a member of the genus PPV because of lack of the genetic characterization of the virus. 2 Moreover, a recent study on eight CCE viruses found that the virus was genetically diverse and showed close similarities to PCPV in addition to ORFV. 3 We believe that the dermoscopic red-pink clods and white network histologically correspond to the viral eosinophilic inclusion bodies and epidermal acanthosis/hypergranulosis, respectively. Our dermoscopic findings with white streaks and linear red-pink clods are similar to those reported in the literature. 4,5 In conclusion, we report a case of orf transmitted from camels. Dermoscopically, linear red-pink clods appear to be a useful feature in the diagnosis of orf. More studies on the clinical and dermoscopic features of orf transmitted from camels are needed.

show abstract

“…The diagnosis of Orf infection is usually confirmed clinically on the grounds of contact history with infected animals together with the characteristic skin lesions on exposed sites of the body. However, skin biopsy and other diagnosed tools, including virus culture, serological testing, transmission electron microscopy, and molecular testing such as PCR-based approaches and sequencing [ 1 , 4 , 14 , 15 ], can assist in the confirmation of the diagnosis in unusual cases. Nowadays, the diagnosis of acute Orf infection is based on PCR analysis of fresh samples (swabs, fluid from blister or pustule, or crusts).…”

Section: Discussionmentioning

confidence: 99%

“…However, PCR technology to detect the DNA or RNA of these pathogens from fresh tissue specimens or paraffin-embedded tissue may be valuable supplements to culture and serology in doubtful cases. Other differential diagnoses include pyogenic granuloma and keratoacanthoma [ 1 , 14 , 18 ].…”

Section: Discussionmentioning

confidence: 99%

Orf Infection on the Scalp of a Taiwanese Woman: A Case Report and Literature Review

Juang

Win

Chen

et al. 2023

Life

View full text Add to dashboard Cite

Background: Orf, or ecthyma contagiosum, is a zoonosis caused by Parapoxvirus that infects sheep and goats. Human transmission typically occurs in persons in contact with the infected animals or contaminated fomites and environment. In humans, it generally occurs as solitary or multiple skin lesions on the hands or fingers. Involvement of the head region has rarely been reported. Case presentation: We report an unusual case with multiple orf lesions on the scalp of a middle-aged woman, along with a review of previously reported Orf cases on the head region. Conclusions: Although Orf infection rarely happens on the head region, it should be considered in the differential diagnosis of cases with relevant animal exposure.

show abstract

Clinical Manifestation, Dermoscopy, and Scanning Electron Microscopy in Two Cases of Contagious Ecthyma (Orf Nodule)

Cited by 6 publications

References 7 publications

Dermoscopy of Bacterial, Viral, and Fungal Skin Infections: A Systematic Review of the Literature

Dermoscopy of Bacterial, Viral, and Fungal Skin Infections: A Systematic Review of the Literature

The challenges of teaching and examining dermatology in the medical school curriculum

Orf Infection on the Scalp of a Taiwanese Woman: A Case Report and Literature Review

Contact Info

Product

Resources

About