Clinical manifestation and associated factors of seborrheic dermatitis in Korea

Park, Seon Yong; Kwon, Hyuck Hoon; Min, Sangkee; Yoon, Ji Young; Suh, Dae Hun

doi:10.1684/ejd.2015.2706

Cited by 12 publications

(14 citation statements)

References 12 publications

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“…Another population‐based study using data from the Rotterdam Study indicated that SD is more prevalent in men, as well as in middle‐aged and elderly people, especially during winter 21 . Two other studies conducted in Korea and Turkey also reported a male‐ and elderly predominant pattern in patients with SD compared with controls 22,23 . We found that SD was more prevalent in men and in elderly participants, which corroborated with previous study findings.…”

Section: Discussionsupporting

confidence: 90%

Seborrheic dermatitis and risk of incident peptic ulcer disease: A nationwide population‐based cohort study

Chen¹,

Lin

Wang

et al. 2021

Aust J Dermatology

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Background Emerging evidence supports a strong association between the skin and the gut. The association between seborrheic dermatitis (SD) and peptic ulcer disease (PUD) was largely unknown. This study aimed to investigate the association of SD and PUD. Methods This nationwide population‐based cohort study was conducted using the Taiwan's National Health Insurance Research Database. A total of 19 445 participants was recruited. Each patient with a diagnosis of incident SD was matched to four patients without SD using propensity scores based on age, gender, index year, insurance amount, urbanisation level, Charlson comorbidity index (CCI), the presence of comorbidities and medication use. The primary endpoint was the development of incident PUD. Hazard ratios (HRs) and corresponding 95% confidence intervals (CIs) for PUD occurrence in relation to the presence of SD were calculated. Results Overall, patients with SD had a significantly higher risk for incident PUD than those without SD in both univariable (crude HR = 1.60, 95% CI 1.38–1.86, P < 0.001) and multivariable (adjusted HR = 1.58, 95% CI 1.36–1.83, P < 0.001) Cox proportional hazard regression models. Kaplan–Meier analysis indicated that the cumulative incidence of PUD was consistently higher in individuals with SD than those without SD (log‐rank test, P < 0.001). A higher risk of PUD was also found in individuals with SD than those without SD in all stratified analyses by age, gender, CCI and follow‐up time. Conclusion Patients with SD may have a higher risk for incident PUD. Further studies are warranted to validate our findings.

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Section: Discussionsupporting

confidence: 90%

Seborrheic dermatitis and risk of incident peptic ulcer disease: A nationwide population‐based cohort study

Chen¹,

Lin

Wang

et al. 2021

Aust J Dermatology

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“…The skin-related comorbidity and the triggering factors determined, support the experience from clinical care and from the few studies published, 3 , 18 , 19 suggesting that acne, seborrheic eczema, folliculitis and rosacea are associated with seborrhea.…”

Section: Discussionsupporting

confidence: 63%

Prevalence and Associated Diseases of Seborrheic Skin in Adults

Kirsten¹,

Mohr²,

Alhumam³

et al. 2021

CLEP

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Background Seborrhea is a skin condition characterized by abundant production of sebum associated with typical dermatological conditions such as rosacea and acne. Little is known about the prevalence of seborrhea and the frequency of concurrent skin diseases in the general population. Objective To investigate the epidemiology and comorbidity of seborrhea in the adolescent and adult working population. Methods In large-scale examinations by dermatologists in 343 German companies, the seborrheic skin type and the occurrence of skin findings were documented electronically. Odds ratios (OR) and their 95% confidence intervals (95% CI) of further skin diseases were computed. Logistic regression analyses were conducted for each disease using seborrhea as dependent variable. Results A total of 48,630 employees were examined. About 6.0% showed seborrhea (6.6% in men, 5.4% in women). Seborrhea strongly predicted acne (OR 3.59; CI 3.18–4.05), trichilemmal cysts (OR 1.99; CI 1.25–3.18) and rosacea (OR 1.45; CI 1.17–1.81). Regression analyses controlling for age, gender and phototype confirmed significant associations of seborrhea with acne and rosacea. Conclusion Only a minor proportion of the working population shows meaningful seborrheic skin. However, this condition predicts distinct skin diseases and thus needs attention, in particular, with respect to consulting and secondary prevention.

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“…Some high‐quality prevalence studies focus on specific age groups such as the Rotterdam Study on an elderly population . Others focus on the systemic comorbidity of seborrhoeic dermatitis . By contrast, data on its association with other skin conditions are scarce.…”

mentioning

confidence: 99%

Epidemiology and dermatological comorbidity of seborrhoeic dermatitis: population‐based study in 161 269 employees

et al. 2019

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Summary Background Seborrhoeic dermatitis is a common but epidemiologically poorly researched chronic skin disease. Objectives To characterize the prevalence and dermatological comorbidity of seborrhoeic dermatitis in Germany. Methods In the course of voluntary company skin checks, full‐body examinations were carried out in more than 500 companies by experienced dermatologists and documented electronically. Results In total, 161 269 participants were included (men 55·5%, mean age 43·2 ± 10·9 years). Seborrhoeic dermatitis was identified in 3·2% (men 4·6%, women 1·4%). A significant difference was found between age groups (2·0% in < 35; 3·6% in 35–64; 4·4% ≥ 65 years). The most frequent concomitant skin conditions were: folliculitis [17·0%, 95% confidence interval (CI) 15·9–18·1], onychomycosis (9·1%, 95% CI 8·3–10·0), tinea pedis (7·1%, 95% CI 6·3–7·8), rosacea (4·1%, 95% CI 3·6–4·7), acne (4·0%, 95% CI 3·4–4·5) and psoriasis (2·7%, 95% CI 2·3–3·2). Regression analysis revealed the following relative dermatological comorbidities when controlling for age and sex: folliculitis [odds ratio (OR) 2·1, 95% CI 2·0–2·3], contact dermatitis (OR 1·8, 95% CI 1·1–2·8), intertriginous dermatitis (OR 1·8, 95% CI 1·4–2·2), rosacea (OR 1·6, 95% CI 1·4–1·8), acne (OR 1·4, 95% CI 1·2–1·7), pyoderma (OR 1·4, 95% CI 1·1–1·8), tinea corporis (OR 1·4, 95% CI 1·0–2·0), pityriasis versicolor (OR 1·3, 95% CI 1·0–1·7) and psoriasis (OR 1·2, 95% CI 1·0–1·5). Conclusions Seborrhoeic dermatitis is a common disease, which is more prevalent in men and older people, and it has an increased rate of dermatological comorbidity. However, absolute differences in the prevalence of comorbidities are small and negligible. Nevertheless, the findings underline the need for integrated, complete dermatological diagnostics and therapy.

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Clinical manifestation and associated factors of seborrheic dermatitis in Korea

Cited by 12 publications

References 12 publications

Seborrheic dermatitis and risk of incident peptic ulcer disease: A nationwide population‐based cohort study

Seborrheic dermatitis and risk of incident peptic ulcer disease: A nationwide population‐based cohort study

Prevalence and Associated Diseases of Seborrheic Skin in Adults

Epidemiology and dermatological comorbidity of seborrhoeic dermatitis: population‐based study in 161 269 employees

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