Clinical management of dural defects: A review

Dong, Rong-Peng; Zhang, Qi; Yang, Lili; Cheng, Xueliang; Zhao, Jianwu

doi:10.12998/wjcc.v11.i13.2903

Cited by 6 publications

(3 citation statements)

References 97 publications

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“…Macrophages possess potent phagocytosis and a lethal capacity, which could swiftly reach the site of infection by penetrating the blood vessel wall through chemotactic media, carrying out the biological processes of microorganism digestion and phagocytosis. 44 Due to the considerable rise in basophila and macrophage levels in CSF, the rabbit brain with dural defect might have been infected with bacteria. Overall, the n HA/PLCL membrane could effectively stop intracranial infections and inflammatory reactions brought on by dural injuries.…”

Section: Resultsmentioning

confidence: 99%

A robust and biodegradable hydroxyapatite/poly(lactide-co-ε-caprolactone) electrospun membrane for dura repair

Wang,

Wu,

Liu

et al. 2024

J. Mater. Chem. B

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Section: Resultsmentioning

confidence: 99%

A robust and biodegradable hydroxyapatite/poly(lactide-co-ε-caprolactone) electrospun membrane for dura repair

Wang,

Wu,

Liu

et al. 2024

J. Mater. Chem. B

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“…When the dura is torn or damaged, the decrease in cerebrospinal fluid (CSF) pressure leads to a series of clinical symptoms often followed by complications such as infections and neurological dysfunction. 9 The first action to take is to rinse thoroughly with saline solution (∼500 mL) to assess the extent of the damage and discuss with the veterinarian the possibility of suturing the dura. Instead, Gelfoam (absorbable gelatin compressed sponge) can be used to cover a small dural incision.…”

Section: Troubleshootingmentioning

confidence: 99%

Protocol for extracellular recordings in the external globus pallidus of the behaving/awake monkey

Katabi,

Israel,

Bergman

et al. 2024

STAR Protocols

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“…The hermetic closure of the dura mater is an essential step in the training of any neurosurgeon; it is an extremely important moment, often undervalued by neurosurgeons in training. The consequence of inadequate closure, often due to insufficient training, can lead to serious complications, such as cerebrospinal fluid (CSF) leak with consequent meningitis and even death [ 1 , 2 ]. Among the complications in neurosurgery, CSF leak is one of the most challenging, often leading to prolonged hospitalization and reoperation.…”

Section: Introductionmentioning

confidence: 99%

Dural Closure Training With Prototyped Model

El Husseini,

Chenisz da Silva,

Giacomelli Leal

et al. 2024

Cureus

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Introduction: The hermetic closure of the dura mater is a critical step in neurosurgical training, often undervalued but crucial to preventing serious complications such as cerebrospinal fluid (CSF) leaks leading to meningitis and death. Inadequate closure, often due to insufficient training, can result in challenging complications, including prolonged hospitalization and reoperation. Objective: To address the deficiencies in dural closure training, this study aims to describe a 3D prototype for simulating post-craniotomy dura mater suturing. The objective is to reduce the incidence of CSF leaks and improve the training of neurosurgery residents. Design: The study involves the creation of a 3D prototype based on magnetic resonance imaging and computed tomography scans. The additive manufacturing of structures is performed using ABS filament, and a silicone rubber membrane is used to simulate the meningeal dura mater. Neurosurgery residents undergo training using this model, and the effectiveness is evaluated. Setting: The study is conducted at the Institute of Neurology of Curitiba (Hospital INC), focusing on neurosurgery residents from the first to fifth year of residency. Participants: Seven residents participate in the study, with varying levels of experience in dural closure procedures. The training involves a simulated surgical environment using the 3D prototype. Results: After training, residents show improvements in confidence and theoretical knowledge related to dural closure. Binary questions indicate a strong desire for more practical training on dural closure, with 85.7% believing in the essential role of 3D molds in their neurosurgery training. Conclusion: The study highlights the importance of adequate training for dural closure to prevent serious complications in neurosurgery. The use of 3D simulation models, despite some limitations, proves to be an effective educational strategy. The emerging technology of bioprinting holds promise for further enhancing simulation materials, bringing medical education closer to realistic tissue replication.

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Clinical management of dural defects: A review

Cited by 6 publications

References 97 publications

A robust and biodegradable hydroxyapatite/poly(lactide-co-ε-caprolactone) electrospun membrane for dura repair

A robust and biodegradable hydroxyapatite/poly(lactide-co-ε-caprolactone) electrospun membrane for dura repair

Protocol for extracellular recordings in the external globus pallidus of the behaving/awake monkey

Dural Closure Training With Prototyped Model

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