Clinical management of chronic inflammatory demyelinating polyneuropathy (CIDP) in Europe and India: An exploratory study

Svačina, Martin K R; Mehndiratta, Man Mohan; Vedeler, Christian A.; Sharma, Yogesh; Bobylev, Ilja; Sprenger, Alina; Remke, Gina; Wüstenberg, Hauke; Klein, Ines; Joshi, Abhijeet; Lehmann, Helmar C.

doi:10.1016/j.jns.2021.117507

Cited by 2 publications

(1 citation statement)

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“…Biogenetic analysis found that lupus nephritis in Asian patients had higher levels of autoantibodies, higher frequency of lupus nephritis and higher prevalence of active glomerulonephritis compared with white patients [44]. At the same time, it was found that the incidence of lupus nephritis in Asian patients was younger (the most common damage in children with SLE was kidney, neuropsychiatric system, optic nerve system and skeletal muscle [45]), system involvement was faster, organ damage was earlier, and neuropsychiatric damage score was more serious at 5 years. Although the sample size of our study is slightly smaller, there may be sampling errors, and are Asian, but for the early diagnosis and treatment of disease provides a scienti c basis, early detection, control and remission of the disease, help to improve the survival rate of patients, increase the possibility of treatment bene t.…”

Section: Comparison Of Genotype and Allele Frequencies Of Vegf Gene R...mentioning

confidence: 99%

VEGF Gene Polymorphism And Study On Genetic Susceptibility Of Neuropsychiatric Lupus

Yang,

Jin,

Liu

et al. 2024

Preprint

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Background: Vascular endothelial growth factor ( VEGF ) plays an important role in the pathogenesis of neuropsychiatric lupus ( NPSLE ), This study was designed for analysis of the relationship between single nucleotide polymorphisms of VEGF gene rs699947, rs10434, rs833070 and genetic susceptibility to NPSLE. Methods: A total of 82 patients diagnosed as NPSLE and without other autoimmune diseases were selected as the NPSLE group (positive group). Non-NPSLE group (positive control group) 166 patients with systemic lupus erythematosus without psychiatric symptoms. According to the principle of age matching with the positive control group, 150 healthy subjects were randomly selectedas the healthy control group (negative control group). The allele and genotype of three SNP loci and the correlation between NPSLE and non-NPSLE were analyzed. Results: 1. The genotype frequencies of GG, GA and AA genotypesat rs10434 locus were statistically significant in NPSLE group, non-NPSLE group and negative control group (P < 0.05). 2. The genotype and allele frequencies of rs699947 and rs833070 loci werenot statistically significant in the NPSLE group, non-NPSLE group and negative control group (P > 0.05). 3. rs10434 locus GG genotype and G gene as reference, A allele, mutant heterozygous model GA, dominant model (GA+AA ) were associated with therisk of NPSLE (P < 0.05). Conclusion: We found that VEGF rs10434 A allele, mutant heterozygous model GA, dominant model GA+AA can increase the risk of NPSLE. A allele and dominant model GA+AA can increase the risk of non-NPSLE. There was no significant correlation between rs699947 and rs833070 polymorphism and the risk of NPSLE and non-NPSLE.

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Section: Comparison Of Genotype and Allele Frequencies Of Vegf Gene R...mentioning

confidence: 99%

VEGF Gene Polymorphism And Study On Genetic Susceptibility Of Neuropsychiatric Lupus

Yang,

Jin,

Liu

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

Current clinical management of CIDP with immunoglobulins in France: An expert opinion

Cintas¹,

Bouhour²,

Cauquil³

et al. 2023

Revue Neurologique

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Clinical management of chronic inflammatory demyelinating polyneuropathy (CIDP) in Europe and India: An exploratory study

Cited by 2 publications

References 20 publications

VEGF Gene Polymorphism And Study On Genetic Susceptibility Of Neuropsychiatric Lupus

VEGF Gene Polymorphism And Study On Genetic Susceptibility Of Neuropsychiatric Lupus

Current clinical management of CIDP with immunoglobulins in France: An expert opinion

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