Clinical literature review of 1858 Crohn's disease cases requiring surgery in China

Peng, Qing-Hai; He, Manqing; Zhang, Cui; Tang, Qin

doi:10.3748/wjg.v21.i15.4735

Cited by 12 publications

(16 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Perforation is considered a serious and potentially life-threatening event and is one of the main indications for emergency surgical intervention. Free perforation is the indication for surgery in up to 16% of the cases of complicated IBD [ 93 , 94 ]. The site of perforation is usually located in the colon in cases of UC, while patients with CD can present with perforation of either the small or large bowel.…”

Section: Resultsmentioning

confidence: 99%

WSES-AAST guidelines: management of inflammatory bowel disease in the emergency setting

et al. 2021

View full text Add to dashboard Cite

Background Despite the current therapeutic options for the treatment of inflammatory bowel disease, surgery is still frequently required in the emergency setting, although the number of cases performed seems to have decreased in recent years. The World Society of Emergency Surgery decided to debate in a consensus conference of experts, the main pertinent issues around the management of inflammatory bowel disease in the emergent situation, with the need to provide focused guidelines for acute care and emergency surgeons. Method A group of experienced surgeons and gastroenterologists were nominated to develop the topics assigned and answer the questions addressed by the Steering Committee of the project. Each expert followed a precise analysis and grading of the studies selected for review. Statements and recommendations were discussed and voted at the Consensus Conference of the 6th World Society of Emergency Surgery held in Nijmegen (The Netherlands) in June 2019. Conclusions Complicated inflammatory bowel disease requires a multidisciplinary approach because of the complexity of this patient group and disease spectrum in the emergency setting, with the aim of obtaining safe surgery with good functional outcomes and a decreasing stoma rate where appropriate.

show abstract

Section: Resultsmentioning

confidence: 99%

WSES-AAST guidelines: management of inflammatory bowel disease in the emergency setting

et al. 2021

View full text Add to dashboard Cite

show abstract

“…23 The median age of 29 years at diagnosis and 32 years at referral to surgery for CD compares well with the 26-45 years reported in the literature. 24 The median age at diagnosis of UC and time of referral for surgery was 35 years and 44 years respectively. International literature reports a delay of 5-9 years before surgical referral.…”

Section: Discussionmentioning

confidence: 99%

A fourteen-year audit of surgery for inflammatory bowel disease at a tertiary colorectal unit

et al. 2021

View full text Add to dashboard Cite

BACKGROUND: In South Africa, inflammatory bowel disease (IBD) is increasing in frequency. The purpose of the study was to document our experience with the surgical management of patients with IBD and describe the cohort undergoing surgical management of IBD in a KwaZulu-Natal province tertiary state sector hospital METHODS: Retrospective analysis of a database of patients undergoing surgery for IBD. Demographics, site and disease duration, surgical indications, management and outcome were analysed RESULTS: Of 397 patients with IBD, 136 had Crohn's disease (Cd) (African 13, Indian 78, Coloured 10 and White 35) and 261 had ulcerative colitis (UC) (African 67, Indian 158, Coloured 9 and White 27). Eighty-six of 136 patients with CD required surgical referral. Ileo-colonic CD was most common and non-stricturing/non-penetrating disease behaviour predominated. Seventy-four patients with CD underwent 76 abdominal surgical procedures with in-hospital mortality of 3.5% and a morbidity of 20.9%. Twenty patients required anorectal fistula procedures. Recurrence occurred in nine patients (10.5%) and malignant transformation was seen in three patients (2.2%). One hundred and sixty-three of the 261 patients with UC had pancolitis. Failed medical management was the most common indication for surgical referral. Fifty-one patients with UC had surgery, (age 44.5 [IQR 27-56] years). Forty-five patients underwent 63 abdominal surgical procedures with an overall mortality of 17.7% and a morbidity of 39.2%. Colorectal cancer was seen in 10 patients (3.8%). Laparoscopic procedures were undertaken in eight CD patients (10.8%) and 29 UC patients (39%). The median hospital stay was 7 days for both open and laparoscopic resection CONCLUSION: IBD is not uncommon in African patients, with UC being more frequent than CD. Postoperative mortality and potential for malignant transformation are higher for UC Keywords: inflammatory bowel disease, Crohn's disease, ulcerative colitis, surgical management

show abstract

“…Severe perianal disease, bleeding, or severe pain are found to be indications for surgery in 3% of cases, whereas in fistulizing disease, these symptoms are indications for surgery in 8% of cases. 5 Oral metronidazole has notable efficacy for treating CD when glucocorticosteroids fail.…”

Section: Discussionmentioning

confidence: 99%

Severe contiguous perianal Crohn's disease

et al. 2016

View full text Add to dashboard Cite

Clinical literature review of 1858 Crohn's disease cases requiring surgery in China

Abstract: AIM:To summarize the clinical characteristics of Crohn's disease (CD) patients who underwent surgery in China.

Cited by 12 publications

References 25 publications

WSES-AAST guidelines: management of inflammatory bowel disease in the emergency setting

WSES-AAST guidelines: management of inflammatory bowel disease in the emergency setting

A fourteen-year audit of surgery for inflammatory bowel disease at a tertiary colorectal unit

Severe contiguous perianal Crohn's disease

Contact Info

Product

Resources

About