Clinical instruction in nursing is an important and integral part of its training program, the clinical instructor's role is the foundation stone in developing and instructing nursing students. The definition of the role of clinical instructor combines a wide variety of roles: nursing roles and areas of responsibility to hospitals versus teaching roles and responsibility to nursing schools, having responsibility for patient care on the one hand and student instruction on the other, and being simultaneously committed to the health system, students and nursing school. The multiple roles of clinical instructors create an overload and tension at work, cause difficulties in setting role priorities, emotional overload, and feelings of guilt. This is likely to produce tension and inherent conflict between clinical nursing instruction roles, to negatively affect job satisfaction and result in resignations from instruction roles. Inherent role conflicts and tensions derive, among others, from contradictions in the nature of the role. On the one hand, clinical instructors develop and mold students, give them tools and teach them skills, while on the other hand, this role is to supervise and evaluate, provide feedback and evaluate students during and after their clinical experience. This article will reveal and discuss the phenomenon of in-role conflict found in clinical instructors' roles.