Clinical Implications of Inflammation in Patients With Cirrhosis
Victoria T. Kronsten,
Debbie L. Shawcross
Abstract:Cirrhosis-associated immune dysfunction refers to the concurrent systemic inflammation and immunoparesis evident across the disease spectrum of chronic liver disease; ranging from the low-grade inflammatory plasma milieu that accompanies compensated disease, to the intense high-grade inflammatory state with co-existent severe immune paralysis that defines acute decompensation and acute-on-chronic liver failure. Systemic inflammation plays a crucial role in the disease course of cirrhosis and is a key driver fo… Show more
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