Abstract:Background: Transcription factor SOX6 belongs to Sry-related high-mobility-group box (SOX) family, has been reported to be downregulated and act as a tumor-suppressor gene in various solid tumors, but in acute myeloid leukemia (AML) is incompletely understood. Methods: The SOX6 expression was analyzed between AML patients and normal controls from public data and our research cohort. Correlations between SOX6 expression and clinical, genetic features together with survival were further analyzed.Results: In both… Show more
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