“…Moreover, the presence or absence of conditions, including frailty, cognitive decline, and orthostatic hypotension, affects the strategies of antihypertensive therapy [7]. Zhang et al conducted a prospective cohort study involving patients aged ≥80 years with acute myocardial infarction to examine how mean BP within 48 h after hospitalization affected cardiovascular death [8]. In their study, ischemic heart disease patients with concomitant hypertension accounted for 77.3% of the participants, and the results showed that cardiovascular mortality was 1.5 times higher in patients with a DBP of less than 65 mmHg.…”