Clinical impact of admission hyperglycemia on in-hospital mortality in acute myocardial infarction patients

Kim, Eun Jung; Jeong, Jin‐Ok; Kim, Ju Han; Ahn, Tae Hoon; Seung, Ki Bae; Oh, Dong Joo; Kim, Hyo–Soo; Gwon, Hyeon Cheol; Seong, In Whan; Hwang, Kyung Kuk; Chae, Shung Chull; Kim, Kwon-Bae; Kim, Young Jo; Soo, Kwang; Oh, Seok Kyu; Chae, Jei Keon

doi:10.1016/j.ijcard.2017.01.095

Cited by 68 publications

(75 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the present study, we provide an estimation of the burden of STEMI patients with hyperglycemia and the associated risks for inhospital mortality. Hyperglycemia with STEMI is a powerful predictor of poor in-hospital outcomes [10]. We found that STEMI patients with hyperglycemia develop more complications such as heart failure, cardiogenic shock, and atherosclerosis compared to euglycemic STEMI patients.…”

Section: Discussionmentioning

confidence: 73%

Prognostic Value of Hyperglycemia on Admission on In-hospital Outcomes in Patients Presenting with ST-elevation Myocardial Infarction

Shahid¹,

Hma²,

Ms³

et al. 2020

Cureus

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 73%

Prognostic Value of Hyperglycemia on Admission on In-hospital Outcomes in Patients Presenting with ST-elevation Myocardial Infarction

Shahid¹,

Hma²,

Ms³

et al. 2020

Cureus

View full text Add to dashboard Cite

“…Rates of PCI were 96.7% in STEMI and 82.7% in NSTEMI, and the success rates were 99.4% and 99.5%, respectively, which were relatively higher in Korea than in Western countries 2) . Patients with culprit left main coronary artery stenosis had higher in-hospital mortality than patients with non-culprit left main coronary artery, but had similar clinical outcome during a 12-month follow-up 34) .…”

Section: Interventional Treatmentmentioning

confidence: 81%

“…The ratio of STEMI/NSTEMI in Korea was reversed in 2012 with higher incidence of NSTEMI than STEMI 1) . Intensive medical treatment including high-intensity statin and new anti-platelet therapy, and percutaneous coronary intervention (PCI) using second generation drug-eluting stents (DES) are commonly used in the treatment of Korean AMI patients 2) .…”

Section: General Trends Of Kamirmentioning

confidence: 99%

Recent Update of Korea Acute Myocardial Infarction Registry (KAMIR)

Sim

Jeong

2017

J Jpn Coron Assoc

Self Cite

View full text Add to dashboard Cite

“…However, certain patients may develop diabetes in the future due to insulin resistance (25,26), while a previous study reported that high blood glucose at admission is unrelated to diabetes in the future (27). Regardless of the association between stress hyperglycaemia and diabetes, a number of studies have demonstrated that stress hyperglycaemia is associated with a poor prognosis in AMI (4,6,7).…”

Section: Discussionmentioning

confidence: 99%

“…It is not fully understood how stress hyperglycemia affects the prognosis of primary PCI (4,6,7). Previous studies have demonstrated that inflammation serves an important role in this process (8)(9)(10).…”

Section: Introductionmentioning

confidence: 99%

Effect of stress hyperglycaemia on monocyte chemoattractant protein‑1 levels and the short‑term prognosis of patients with acute ST‑segment elevation myocardial infarction undergoing primary percutaneous coronary intervention

2019

View full text Add to dashboard Cite

The present study prospectively investigated the effect of blood glucose level at admission on monocyte chemoattractant protein-1 levels at different time points before and after primary percutaneous coronary intervention, and the postoperative 1-year prognosis of patients with acute ST-segment elevation myocardial infarction. The 146 patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention were divided into three groups: Group 1, non-diabetic, non-hyperglycemic group; group 2, stress hyperglycemia group; and group 3, diabetic group. Serum monocyte chemoattractant protein-1 levels before and after percutaneous coronary intervention (PCI), and the incidence of major adverse cardiovascular events 1-year post PCI were observed. The increase in monocyte chemoattractant protein-1 levels 24 h after percutaneous coronary intervention, compared with those before percutaneous coronary intervention, was significantly correlated with the blood glucose level at admission. Furthermore, the 1-year postoperative major adverse cardiovascular events rates were significantly higher in groups 2 and 3 compared with group 1. Logistic regression analysis demonstrated that a high blood glucose level at admission, diabetes, and high preoperative monocyte chemoattractant protein-1 levels were risk factors for major adverse cardiovascular events 1-year post-percutaneous coronary intervention. Stress hyperglycemia and diabetes may contribute to high monocyte chemoattractant protein-1 levels and prolonged inflammation. These symptoms are associated with poor prognosis of acute ST-segment elevation myocardial infarction in patients undergoing primary percutaneous coronary intervention.

show abstract

Clinical impact of admission hyperglycemia on in-hospital mortality in acute myocardial infarction patients

Cited by 68 publications

References 38 publications

Prognostic Value of Hyperglycemia on Admission on In-hospital Outcomes in Patients Presenting with ST-elevation Myocardial Infarction

Prognostic Value of Hyperglycemia on Admission on In-hospital Outcomes in Patients Presenting with ST-elevation Myocardial Infarction

Recent Update of Korea Acute Myocardial Infarction Registry (KAMIR)

Effect of stress hyperglycaemia on monocyte chemoattractant protein‑1 levels and the short‑term prognosis of patients with acute ST‑segment elevation myocardial infarction undergoing primary percutaneous coronary intervention

Contact Info

Product

Resources

About