Clinical, genetic and microbiological findings in a Brazilian family with aggressive periodontitis

Abstract

The results show that the present microbiological and genetic parameters were not relevant for the prediction of periodontitis susceptibility in this family.

Association of Single Nucleotide Gene Polymorphism at Interleukin‐1β +3954, −511, and −31 in Chronic Periodontitis and Aggressive Periodontitis in Dravidian Ethnicity

“…The genotype and allele distribution of IL‐1β −511, −31 and +3954 SNPs revealed no statistically significant difference, even between the group with aggressive periodontitis and the control group. This result with IL‐1β −511 and −31 is consistent with findings in a Greek population 31 and a Brazilian population 32 . Our results on IL‐1β +3954 polymorphism are consistent with findings in many different populations of Japanese, 10 African American, 11 white, 11,33,34 Greek, 35 and Chinese 36 origin.…”

Gene polymorphism and protein of human pro- and anti-inflammatory cytokines in Chinese healthy subjects and chronic periodontitis patients

“…Higher allele 2 frequency was observed in patients with chronic periodontitis than in healthy individuals [22]. Aggressive periodontitis was not linked to this locus [23-25]. The remaining promoter polymorphisms were not associated with periodontitis, apart from one study that found an association between the -1031, -863, -857 SNPs and chronic periodontitis severity in the Japanese population [23,26,27].…”

Diversidade bacteriana por análise clonal de 16S rRNA e pela hidridação DNA-DNA em amostras de biofilme subgengival de indivíduos portadores de periodontite agressiva.

“…actinomycetemcomitans (HAN et al, 1991;KAMMA et al 2001;MULLALLY et al, 2000;LOPEZ et al, 1996;TREVILATTO et al, 2002;KAMMA et al, 2004 (DARBY et al, 2000;KURU et al, 1999;MULLALLY et al, 2000;KAMMA et al, 2004;XIMENEZ-FYVIE et al, 2006).…”

“…Embora A. actinomycetemcomitans seja considerado como o principal patógeno na doença periodontal agressiva, existem algumas controvérsias na literatura (HAN et al, 1991;LOPEZ et al, 1996;MULLALLY et al, 2000;KAMMA et al, 2001;ISHIKAWA et al, 2002;TREVILATTO et al, 2002;TAKEUCHI et al, 2003;GAJARDO et al, 2005 Inúmeros métodos têm sido utilizados para a identificação dos microrganismos bucais. As técnicas de microscopia de contraste de fase e de campo escuro podem demonstrar diferenças de tamanho, forma e motilidade dos microrganismos presentes no biofilme dental.…”