2006
DOI: 10.1590/s0074-02762006000700005
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Clinical forms of Trypanosoma cruzi infected individuals in the chronic phase of Chagas disease in Puebla, Mexico

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Cited by 30 publications
(15 citation statements)
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“…In Brazil and other countries in southern South America, TcI is less frequent in chronic chagasic patients, but most patients from Panama, Colombia, Ecuador, and Venezuela have been found to be infected with this DTU (Añez et al, 2004;Sousa et al, 2006;Herrera et al, 2007;Falla et al, 2009;Ocaña-Mayorga et al, 2010). Instances of patients infected with TcI who show severe cardiomyopathy have been reported from Colombia, Venezuela, and Paraíba state in northeastern Brazil, as well as from Mexico (Añez et al, 2004;Zafra et al, 2008;Ramírez et al, 2010), including severe clinical manifestations and even fatalities Sánchez-Guillén et al, 2006). In the present study, the classification of isolate PR-150 as TcI, by means of the rRNA and COII/RFLP, is compatible with the complete resistance of this isolate to benznidazole (Toledo et al, 1997).…”
Section: Discussionmentioning
confidence: 99%
“…In Brazil and other countries in southern South America, TcI is less frequent in chronic chagasic patients, but most patients from Panama, Colombia, Ecuador, and Venezuela have been found to be infected with this DTU (Añez et al, 2004;Sousa et al, 2006;Herrera et al, 2007;Falla et al, 2009;Ocaña-Mayorga et al, 2010). Instances of patients infected with TcI who show severe cardiomyopathy have been reported from Colombia, Venezuela, and Paraíba state in northeastern Brazil, as well as from Mexico (Añez et al, 2004;Zafra et al, 2008;Ramírez et al, 2010), including severe clinical manifestations and even fatalities Sánchez-Guillén et al, 2006). In the present study, the classification of isolate PR-150 as TcI, by means of the rRNA and COII/RFLP, is compatible with the complete resistance of this isolate to benznidazole (Toledo et al, 1997).…”
Section: Discussionmentioning
confidence: 99%
“…It is said that up to 30–40% of infected people will develop cardiac or digestive involvement during their life . These data are based on classical series from endemic areas and mostly published before 1990 . The most recent published series of chronic Chagas disease in non‐endemic countries show a different clinical profile, with younger patients and lower morbidity .…”
Section: Introductionmentioning
confidence: 99%
“…Its distribution extends from the southern USA to southern Latin America and it is estimated that 16-18 million people are infected and 100 million at risk of infection [1]. In immunocompetent patients, the parasite load decreases after the acute infection but persists at low levels during the chronic phase [5,6] and patients might develop visceral pathologies, possibly as a result of persistent infection and immune reactivation [7,8]. Patients with acute T. cruzi infection achieve high levels of parasitemia, regardless of their immune status.…”
Section: Trypanosoma and Hivmentioning
confidence: 99%