2023
DOI: 10.55544/jrasb.2.3.18
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Clinical Features Present, Past & Future Prospective of Monkey Pox: A Orthopoxvirus

Siddhartha Shukla,
Naveen Rawat,
Sarthak Rana
et al.

Abstract: Some issues regarding the potential spread of monkeypox have arisen just as the international world is beginning to recover from the initial alarm that was caused by the probable spread of coronavirus disease 2019 (COVID-19). Despite the fact that parts of Africa have traditionally been more susceptible to monkeypox than other regions of the world, the majority of new cases that have been linked to the outbreak that began in 2022 have been reported in countries located in Europe and the western hemisphere. Des… Show more

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Cited by 5 publications
(2 citation statements)
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“…According to another study, SNHG16 enhances hRMEC apoptosis by regulating E2F transcription factor-1 (E2F1) expression through sponging miR-20a-5p [50]. The direct effects of excessive glucose on retinal neurons, glial cells, and blood vessels [51] are mediated by E2F1, and E2F1 regulates oxidative metabolism [52]. More than that, by influencing the miR-195/mitofusin 2 (mfn2) axis, SNHG16 heightens oxidative stress-induced pathological angiogenesis in hMRECs.…”
Section: Snhg16mentioning
confidence: 99%
See 1 more Smart Citation
“…According to another study, SNHG16 enhances hRMEC apoptosis by regulating E2F transcription factor-1 (E2F1) expression through sponging miR-20a-5p [50]. The direct effects of excessive glucose on retinal neurons, glial cells, and blood vessels [51] are mediated by E2F1, and E2F1 regulates oxidative metabolism [52]. More than that, by influencing the miR-195/mitofusin 2 (mfn2) axis, SNHG16 heightens oxidative stress-induced pathological angiogenesis in hMRECs.…”
Section: Snhg16mentioning
confidence: 99%
“…Thus, damage propagates from the original site to neural projections in trans-synaptic degeneration. Retrograde trans-synaptic degeneration in the human visual system, specifically in relation to glaucoma, has only been brought to light in the last few decades, while it has long been established in the motor system and cerebellar pathways [52,53,54]. It exacerbates the vision problems seen in people with a wide range of disorders, including MS [55].…”
Section: Cns and Eye Neurodegenerationmentioning
confidence: 99%