Abstract:Hepatotoxicity associated with the administration of voriconazole (VRCZ) is a treatment-related adverse event that necessitates discontinuation of administration in some cases. This study is aimed at investigating the clinical features of VRCZ-induced hepatotoxicity in pediatric patients, including the status of hepatic damage before the administration of VRCZ. Demographic and laboratory data were retrieved retrospectively from the medical records of 13 Japanese pediatric patients who underwent VRCZ therapy. B… Show more
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