Clinical features of recurrent Mycoplasma pneumoniae–induced rash and mucositis

Abstract

Mycoplasma pneumoniae (Mp) is a common cause of respiratory infections, which are accompanied by mucocutaneous manifestations in 20%-30% of cases. 1 These include Mycoplasma pneumoniae-induced rash and mucositis (MIRM), a condition distinct from the syndromes of erythema multiforme (EM) and Stevens-Johnson Syndrome (SJS) in terms of pathophysiology, presentation, treatment, and outcomes. 2 MIRM occurs secondary to an active Mp infection with prodromal symptoms of cough,

Recurrent reactive infectious mucocutaneous eruption (RIME) in two adolescents triggered by several distinct pathogens including SARS‐CoV‐2 and influenza A

“…A review of recurrent RIME cases showed that most cases started with an initial MP infection (Table 1 ). 6 , 8 , 9 , 11 , 12 Future studies could investigate whether persistently elevated antibodies from non‐MP pathogens could also increase risk of recurrence.…”

“…Recurrent episodes are poorly understood. Reports have estimated a recurrence rate ranging from 9% to 38% 9 . In this report, we describe in detail two cases of recurrent RIME with initial episodes suspected to be triggered by MP.…”

“…Reports have estimated a recurrence rate ranging from 9% to 38%. 9 In this report, we describe in detail two cases of recurrent RIME with initial episodes suspected to be triggered by MP. Subsequent episodes were caused by other viral infections including SARS‐CoV‐2 and influenza A.…”

Virale Exantheme im Kindesalter

“…Nichtsdestotrotz führten diese teilweise auch zu Hospitalisierungen und verlängertem Krankheitsverlauf. Zwischen den Rezidiven lagen Zeitspannen von 2 Monaten bis zu 2 Jahren [ 28 ]. Ferner sind auch bei viral induzierten RIME Rezidive beschrieben, unter anderem 2 Fallberichte, in denen die initialen Episoden am ehesten durch Mycoplasma pneumoniae getriggert und die Rezidive teils durch Viren wie Influenza A und SARS-CoV‑2 ausgelöst wurden [ 50 ].…”

Phát ban và viêm niêm mạc do Mycoplasma pneumoniae có thể nhầm lẫn với tình trạng dị ứng: Báo cáo ca bệnh

“…MIRM gặp chủ yếu ở trẻ em, nam gặp nhiều hơn nữ (nam chiếm 2/3 tổng số trường hợp). 1,2,3 Cho đến nay, nguyên nhân gây ra MIRM chưa được biết đến chính xác. Một số giả thuyết cho rằng M. pneumoniae trực tiếp gây tổn thương các tế bào ở da và niêm mạc, một số giả thuyết khác lại cho rằng M. pneumoniae gián tiếp gây tổn thương thông qua cơ chế miễn dịch.…”