Clinical features of recurrent and insidious chronic bird fancier's lung

Ohtani, Yoshio; Saiki, Shigeki; Sumi, Yuki; Inase, Naohiko; Miyake, Shuji; Costabel, Ulrich; Yoshizawa, Yasuyuki

doi:10.1016/s1081-1206(10)61863-7

Cited by 122 publications

(69 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, in high-risk occupations, the prevalence of HP is between 5-15% exposed to a known antigen. For example, the prevalence of farmer's lung is 2-8% of exposed individuals (Lopez and Salvaggio, 1987), while 6-21% of pigeon breeders get HP and 15% (Ohtani et al, 2003) of people exposed to humidification systems developed HP (Baur et al, 1992). In one instance up to 70% of individuals exposed to building with a contaminated ventilation system developed HP (Hodgson et al, 1987).…”

Section: Hypersensitivity Pneumonitismentioning

confidence: 99%

Environmental, Inhaled and Ingested Causes of Pulmonary Fibrosis

et al. 2007

View full text Add to dashboard Cite

Pulmonary fibrosis is a general term that refers to a collection of connective tissue around alveolar structures. There are over 200 disorders where the lungs may be involved in a fibrotic response. To determine the cause of pulmonary fibrosis requires an in depth understanding of the pathogenesis of pulmonary fibrosis and breadth of knowledge of the causative agents and associated disorders that may lead to pulmonary fibrosis. A comprehensive evaluation of the patient is absolutely essential, starting with detailed history that includes an occupational and environmental history because fibrogenic exposures can occur in many settings. Equally important is a history of ingestion of pharmaceutical or nonpharmaceutical substances. A physical examination and judicious investigations are always a part of any comprehensive clinical assessment but they are not commonly helpful in elucidating the cause of most pulmonary fibrotic disorders. Although, a chest film is invariably done, a logical and strongly recommended next step is a high-resolution computed tomography (HRCT). HRCT provides a better assessment of the radiological pattern, may suggest a diagnosis as well as direct the site, and type of lung biopsy. If the history and investigations do not lead to a diagnosis then a lung biopsy is required. Prevention or removal of the inciting agent is critical to the treatment of these disorders and in some instances corticosteroids may be of help.

show abstract

Section: Hypersensitivity Pneumonitismentioning

confidence: 99%

Environmental, Inhaled and Ingested Causes of Pulmonary Fibrosis

et al. 2007

View full text Add to dashboard Cite

show abstract

“…Pathological findings by surgical lung biopsy indicated that many cases of CHP patients predominantly showed interstitial fibrosis with a usual interstitial pneumonia (UIP) pattern (2,12). The present patient underwent right upper lobectomy, which showed a fibrotic change.…”

Section: Discussionmentioning

confidence: 59%

“…The diagnosis of insidious CHP is obviously more difficult than recurrent CHP. But, the inhalation provocation test is useful for the diagnosis of chronic bird fancier's lung including the recurrent and insidious types (2,8). In home-related HP, the identification of a particular antigen may be difficult, so the inhalation provocation test is seldom performed.…”

Section: Discussionmentioning

confidence: 99%

“…The clinical features of HP are classically divided into three subtypes; acute, subacute, and chronic (1). Chronic HP (CHP) is further divided into two groups; recurrent acute onset type and insidious type (2,3). The clinical features, radiological findings, pulmonary functions, and prognosis of the insidious type strongly resemble those of idiopathic pulmonary fibrosis (IPF) (2,4).…”

Section: Introductionmentioning

confidence: 99%

“…Chronic HP (CHP) is further divided into two groups; recurrent acute onset type and insidious type (2,3). The clinical features, radiological findings, pulmonary functions, and prognosis of the insidious type strongly resemble those of idiopathic pulmonary fibrosis (IPF) (2,4). CHP develops pulmonary fibrosis after a prolonged period of repeated exposure and persistent inflammation (3,5,6).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Chronic Hypersensitivity Pneumonitis Caused by Aspergillus Complicated with Pulmonary Aspergilloma

et al. 2004

View full text Add to dashboard Cite

show abstract

Environmental levels of avian antigen are relevant to the progression of chronic hypersensitivity pneumonitis during antigen avoidance

Sema

Miyazaki²,

Tsutsui³

et al. 2017

Immunity Inflam & Disease

Self Cite

View full text Add to dashboard Cite

BackgroundIn chronic hypersensitivity pneumonitis (chronic HP), antigen avoidance is critical for disease management; however, complete avoidance is difficult because of unrecognized exposure to antigens. Recently, we revealed that the amount of avian antigen (AAA) in household dust at the time of diagnosis predicted the progression of chronic bird‐related HP. The purpose of this study is to evaluate the relationship between the prognosis of chronic bird‐related HP and the AAA that remained in the environment during antigen avoidance.MethodsFirst, we measured the AAA in household dust of 28 consecutive patients (22 with chronic bird‐related HP and 6 with acute bird‐related HP) and 12 healthy volunteers. Second, we measured the AAA and collected questionnaires on the environmental conditions of the homes of 53 patients with various lung diseases, including bird‐related HP, to investigate the environmental parameters related to a higher AAA. Finally, we prospectively recruited 14 consecutive patients with chronic bird‐related HP, measured the AAA periodically, and collected clinical data.ResultsThe AAA was higher in patients with chronic bird‐related HP at the time of diagnosis compared to healthy volunteers and was highest in patients with acute bird‐related HP. Logistic regression analysis showed that birds frequenting a residence was the only significant factor for a higher AAA (odds ratio, 5.686; 95%CI, 1.263–25.59; P = 0.024). There was a correlation between the mean AAA and decline of vital capacity for 1 year (r = −0.55; 95%CI −0.84 to −0.01; P = 0.043).ConclusionMeasurements of the AAA after diagnosis predict the progression of chronic bird‐related HP. Avian antigen can exist in the indoor environment regardless of antigen avoidance. The presence of avian antigen in the indoor environment can be attributed to wild birds found outdoors.

show abstract

Clinical features of recurrent and insidious chronic bird fancier's lung

Cited by 122 publications

References 28 publications

Environmental, Inhaled and Ingested Causes of Pulmonary Fibrosis

Environmental, Inhaled and Ingested Causes of Pulmonary Fibrosis

Chronic Hypersensitivity Pneumonitis Caused by Aspergillus Complicated with Pulmonary Aspergilloma

Environmental levels of avian antigen are relevant to the progression of chronic hypersensitivity pneumonitis during antigen avoidance

Contact Info

Product

Resources

About