Clinical features of pediatric patients with COVID-19: a report of two family cluster cases

Abstract

Background Coronovirus disease 2019 has spread rapidly across the globe. People of all ages are susceptible to COVID-19. However, literature reports on pediatric patients are limited. Methods To improve the recognition of COVID-19 infection in children, we retrospectively reviewed two confirmed pediatric cases from two family clusters. Both clinical features and laboratory examination results of the children and their family members were described. Results The two confirmed children only presented with mild respiratory or gastrointestinal symptoms. Both of them had normal chest CT images. After general and symptomatic treatments, both children recovered quickly. Both families had travel histories to Hubei Province. Conclusions Pediatric patients with COVID-19 are mostly owing to family cluster or with a close contact history. Infected children have relatively milder clinical symptoms than infected adults. We should attach importance to early recognition, early diagnosis, and early treatment of infected children.

A single-center, retrospective study of COVID-19 features in children: a descriptive investigation

“…The symptoms in children with COVID-19 infection have been well described in the literature [9][10][11][12][13][14][15][16][17][18]. Our results are consistent with these previous reports.…”

“…The most common pattern of chest CT is groundglass opacities, followed by local patchy shadowing and then local bilateral patchy shadowing, which is consistent with published data [9][10][11][12][13][14][15][16][17][18]. Our study indicates that chest CT manifested with a predominance of lesions in the subpleural area (41 [95%] of 43) and in lower lung lobes (28 [65%] of 43), especially in the posterior segment (22 [78%] of 28), an area with a relatively dense amount of bronchioles, blood vessels, and alveoli.…”

“…Compared to adults [3][4][5][6][7], there are a few studies on the COVID-19 in children. Although mortality in children has been reported [8], studies have demonstrated that COVID-19 is generally less severe compared to adults in terms of both symptoms and computerized tomography (CT) manifestations [9][10][11][12][13][14][15][16][17][18]. The common chest CT patterns are ground-glass opacities (GGO) followed by local bilateral shadowing (LPS), in contrast to a large percentage of bilateral patchy shadowing (BPS) pattern in adults [19,20].…”

Clinical features of the first cases and a cluster of Coronavirus Disease 2019 (COVID-19) in Bolivia imported from Italy and Spain

“…As has occurred in other affected countries elsewhere, there is a risk of local clusters of transmission from imported cases [1,[43][44][45][46]. Precisely, the first case in Bolivia, originated the transmission to other seven cases in two different departments of the country, as the patient travelled to Santa Cruz, Cochabamba, La Paz and Oruro (Fig.…”

Modelling the COVID-19 epidemic and implementation of population-wide interventions in Italy

“…Because Italy is on lockdown, extended emergency measures nationwide are being applied to contain the epidemic: unless indispensable for fundamental activities, people are forced to stay at home in family settings, drastically reducing the risk of spreading the disease. Person-to-person household transmission of SARS-CoV-2 has been described in China 44,45 . Although the infection of household members of COVID-19-positive individuals is possible, the rate of this occurrence is difficult to estimate so far.…”