Clinical Features of Patients with Anaphylaxis at a Single Hospital

Park, Hyang Mi; Noh, Jin Chul; Park, Jong Hyun; Won, Youn Kyoung; Hwang, Se Hee; Kim, Jae Yoon; Kim, You Young; Roh, Eui Jung; Chung, Eun Hee

doi:10.7581/pard.2012.22.3.232

Cited by 6 publications

(1 citation statement)

References 26 publications

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“…While eggs and cow milk in children younger than 2 years old was the most common cause of food anaphylaxis. In European and American studies similar to our study, peanut and other nuts are the most common cause of food anaphylaxis,2526272829 while in a study conducted in Korea the most commonly causes included buckwheat, fish, and eggs 30. The difference in anaphylaxis factor probably in these studies is related to the style and habit of food in different regions.…”

Section: Discussionsupporting

confidence: 80%

A survey of anaphylaxis etiology and treatment

et al. 2018

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Identifying the causes of anaphylaxis which is an acute, potentially fatal systemic reaction is very important in every community. Treatment strategies and pitfalls should also be determined. We sought to determine the most common triggers of anaphylaxis, clinical manifestations and treatment strategies in Mashhad, northeast of Iran. An observational cross-sectional study was conducted to evaluate all patients with a history of anaphylactic reaction who were referred to University Allergy Clinics between 2006 and 2016 in Mashhad Iran. We used a combination of patient’s clinical history and allergy diagnostic testing including radioallergosorbant test and skin prick test in order to determine the etiology of anaphylaxis. We identified 172 anaphylactic reactions in 70 patients. Median age was 15 years with a range from 6 months to 48 years. The triggers included: foods, 61.4%; drugs, 15.7%; hymenoptera venom, 8.6%; idiopathic, 5.7%; immunotherapy, 4.3% and other etiologies: 5.7%. Nuts and seeds were the most important triggers of food induced anaphylaxis, especially in school children, adolescents and young adults, followed by fruits. However, Cow’s milk and hen’s egg were the main triggers of anaphylaxis in children aged under 2 years. The most common symptoms were cutaneous and cardiovascular. Corticosteroids (94.3%) and/or antihistamines (85.7%) were used most frequently for treatment followed by intravenous fluids (54.3%), whereas epinephrine was only used in 17.1% of the cases. Food related anaphylaxis and other typical triggers of anaphylaxis are age dependent and the risks and triggers change with age. Epinephrine injection should be increased by improving the awareness of physician and medical teams. The study was approved by the Ethics Committee of the Faculty of Medicine of Mashhad University of Medical Sciences (approved number: IR.MUMS.REC.1393.960).

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Section: Discussionsupporting

confidence: 80%

A survey of anaphylaxis etiology and treatment

et al. 2018

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Comparison of Anaphylaxis and Angioedema with Oral Mucosal Involvement in a Single Pediatric Emergency Department

et al. 2015

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Age group characteristics of clinical features and use of epinephrine in children with anaphylaxis who visited emergency department

Baek¹,

Lee²,

Ryu³

2019

Pediatr Emerg Med J

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Purpose: Diagnosis of anaphylaxis depends on clinical manifestations and a high index of suspicion, and a misdiagnosis can lead to a preventable death. We aimed to investigate age group characteristics of clinical features and epinephrine use in children with anaphylaxis who visited the emergency department (ED). Methods: We performed a retrospective chart review of 138 children who visited a tertiary care hospital ED from January through December 2018, and were discharged with anaphylaxis as the diagnosis. Anaphylaxis was defined according to the National Institutes of Allergy and Infectious Disease criteria. The children were divided into 4 age groups; infants (< 1 year), preschoolers (1-5 years), schoolers (6-11 years), and adolescents (12-18 years). Clinical features and epinephrine use were compared among the age groups. Results: Of the 138 children with presumed anaphylaxis, 108 met the criteria. The most common cause was food (74%), followed by drugs (10.2%). Epinephrine was used in 82 children (75.9%). The infants and preschoolers reported less frequent cardiovascular symptoms (0%-3.6% vs. 26.5%, P = 0.020) and epinephrine use (33.3%-70.9% vs. 91.2%, P = 0.037) compared to the adolescents. The former 2 age groups reported food as triggers more frequent, and often reported foodassociated and respiratory or gastrointestinal symptoms. Conclusion: Infants and preschoolers with anaphylaxis may undergo less frequent cardiovascular symptoms and epinephrine use compared to adolescents. This feature prompts to increased epinephrine use in the former age groups even without ageadjusted hypotension.

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Clinical Features of Patients with Anaphylaxis at a Single Hospital

Cited by 6 publications

References 26 publications

A survey of anaphylaxis etiology and treatment

A survey of anaphylaxis etiology and treatment

Comparison of Anaphylaxis and Angioedema with Oral Mucosal Involvement in a Single Pediatric Emergency Department

Age group characteristics of clinical features and use of epinephrine in children with anaphylaxis who visited emergency department

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