Clinical features, health‐related quality of life, and adult voice in juvenile‐onset recurrent respiratory papillomatosis

Ilmarinen, Taru; Nissilä, Heljä; Rihkanen, Heikki; Roine, Risto P.; Pietarinen-Runtti, Petra; Pitkäranta, Anne; Aaltonen, Leena‐Maija

doi:10.1002/lary.21332

Cited by 23 publications

(20 citation statements)

References 19 publications

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“…However, six adult RRP patients (22%) revealed a normal voice quality (VHI total score < 20). The vast majority of the RRP population in northern Sweden (59%) experienced a moderate to severe voice dysfunction, while the remaining subjects reported minimal voice handicap, consistent with previous studies [18][19][20].…”

Section: Discussionsupporting

confidence: 85%

Voice and quality of life in patients with recurrent respiratory papillomatosis in a northern Sweden cohort

Loizou

Laurell

Lindquist

et al. 2014

Acta Oto-Laryngologica

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Patients that underwent more than one operation per year were younger (p = 0.028) than those treated less frequently. The mean VHItotal score in patients with RRP was 39.3, indicating a statistically significant impairment of voice quality (p < 0.001) as compared with normal subjects. Voice dysfunction was observed in 21 patients (78%). Significantly lower values than the normal population regarding the quality of life in patients with RRP were obtained in the domain of social functioning (p = 0.029). Females, patients with frequent surgical treatment sessions and patients with the high-risk HPV types scored significantly lower in several domains of the quality of life assessment as compared with normal subjects. The results should be interpreted with caution due to the limited number of subjects.

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Section: Discussionsupporting

confidence: 85%

Voice and quality of life in patients with recurrent respiratory papillomatosis in a northern Sweden cohort

Loizou

Laurell

Lindquist

et al. 2014

Acta Oto-Laryngologica

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“…The usefulness of this 15D instrument has been tested in oncologically treated head and neck cancer patients [8] as well as among benign head and neck conditions (juvenileonset recurrent respiratory papillomatosis, septoplasty, tonsillectomy) [17][18][19]. It enables comparisons between different health conditions as well as between general populations [12].…”

Section: Discussionmentioning

confidence: 99%

Trends in the 15D health-related quality of life over the first year following diagnosis of head and neck cancer

Aro

Bäck

Loimu

et al. 2015

Eur Arch Otorhinolaryngol

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Management of head and neck cancer influences both physical and mental wellbeing. Measuring the health-related quality of life (HRQoL) is important, as various treatment modalities are associated with significant morbidity and mortality. In this prospective cohort study, we tested the feasibility of the generic 15D HRQoL instrument in 214 head and neck cancer patients managed with surgery, definitive (chemo)radiotherapy, or with combined modality treatment. HRQoL was assessed at baseline and three times after treatment onset during 1 year, and compared with that of general population standardized for age and sex. At baseline, the patients' mean 15D score was significantly worse compared with general population. Overall HRQoL was at lowest at 3 months after treatment onset, it gradually improved towards 12 months but never reached baseline levels. The dimensions "vitality", "distress", "depression" and "sexual activity" showed marked deterioration at 3 months after the treatment onset, but improved gradually during 12 months. The 15D instrument seems useful for evaluation of HRQoL of head and neck cancer patients. Dimensions reflecting mental wellbeing improved gradually after 3 months, but they seldom reached baseline levels. The support for patients at the time of diagnosis, during treatment, and recovery is emphasized.

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“…6,7 Although they still experienced significant voice problems, JoRRP patients reported only slightly lower QoL in their adult life. 8 Two studies in adults, including both JoRRP and AoRRP patients, confirmed that patients experience more voice problems than the general population. 9,10 Both studies showed that in particular, social functioning was impaired.…”

Section: Introductionmentioning

confidence: 88%

“…Two studies in children showed worse health‐related QoL, impaired social functioning, and lower psychosocial health status . Although they still experienced significant voice problems, JoRRP patients reported only slightly lower QoL in their adult life . Two studies in adults, including both JoRRP and AoRRP patients, confirmed that patients experience more voice problems than the general population .…”

Section: Introductionmentioning

confidence: 92%

Quality of life of patients with recurrent respiratory papillomatosis

et al. 2016

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Clinical features, health‐related quality of life, and adult voice in juvenile‐onset recurrent respiratory papillomatosis

Abstract: JORRP is a risk factor for permanent laryngeal pathology and voice-disturbances in adulthood.

Cited by 23 publications

References 19 publications

Voice and quality of life in patients with recurrent respiratory papillomatosis in a northern Sweden cohort

Voice and quality of life in patients with recurrent respiratory papillomatosis in a northern Sweden cohort

Trends in the 15D health-related quality of life over the first year following diagnosis of head and neck cancer

Quality of life of patients with recurrent respiratory papillomatosis

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