Clinical Features, Epidemiology, and Climatic Impact of Genotype-specific Human Metapneumovirus Infections: Long-term Surveillance of Hospitalized Patients in South Korea

Lim, Yong Kwan; Kweon, Oh Joo; Kim, Hye Ryun; Kim, Tae‐Hyoung; Lee, Mi-Kyung

doi:10.1093/cid/ciz697

Cited by 22 publications

(29 citation statements)

References 29 publications

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“…The meteorological data were collected from the database of Korea Meteorological Administration (KMA; https://data.kma.go.kr/ ). The KMA provides high-resolution meteorological information for specific areas on a flexible web-based platform 20 , 21 . Additionally, we collected the daily records on ten basic meteorological factors, including average temperature, maximum temperature, minimum temperature, ground temperature, diurnal temperature variation, amount of rainfall, wind speed, relative humidity, atmospheric pressure, and duration of sunshine.…”

Section: Methodsmentioning

confidence: 99%

The impact of environmental variables on the spread of COVID-19 in the Republic of Korea

Lim

Kweon

Kim

et al. 2021

Sci Rep

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Corona virus disease 2019 (COVID-19) has been declared a global pandemic and is a major public health concern worldwide. In this study, we aimed to determine the role of environmental factors, such as climate and air pollutants, in the transmission of COVID-19 in the Republic of Korea. We collected epidemiological and environmental data from two regions of the Republic of Korea, namely Seoul metropolitan region (SMR) and Daegu-Gyeongbuk region (DGR) from February 2020 to July 2020. The data was then analyzed to identify correlations between each environmental factor with confirmed daily COVID-19 cases. Among the various environmental parameters, the duration of sunshine and ozone level were found to positively correlate with COVID-19 cases in both regions. However, the association of temperature variables with COVID-19 transmission revealed contradictory results when comparing the data from SMR and DGR. Moreover, statistical bias may have arisen due to an extensive epidemiological investigation and altered socio-behaviors that occurred in response to a COVID-19 outbreak. Nevertheless, our results suggest that various environmental factors may play a role in COVID-19 transmission.

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Section: Methodsmentioning

confidence: 99%

The impact of environmental variables on the spread of COVID-19 in the Republic of Korea

Lim

Kweon

Kim

et al. 2021

Sci Rep

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“…In urban Italy, childhood infections with RSV were negatively correlated with temperature while positively correlated with humidity (34). Human metapneumovirus in Korea peaked between weeks 15 and 20 (35)(36)(37)(38) which is later than for the UK (39). In China, human metapneumovirus infections were associated with sunshine duration, wind speed and diurnal temperature variation (39), and human bocavirus showed both summer and winter increases in different years (40).…”

Section: Discussionmentioning

confidence: 98%

Coronavirus Seasonality, Respiratory Infections and Weather

Nichols

Gillingham

Macintyre

et al. 2020

Preprint

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Background: The survival of coronaviruses are influenced by weather conditions and seasonal coronaviruses are more common in winter months. We examine the seasonality of respiratory infections in England and Wales and the associations between weather parameters and seasonal coronavirus cases.Results: The seasonal distribution of 985,524 respiratory infections in England and Wales (1989-2019) showed coronavirus infections had a similar seasonal distribution to influenza A and bocavirus, with a winter peak between weeks 2-8. Seasonal coronaviruses from 2012 to 2019 were compared to weather parameters for the 28-day average before the patient’s specimen date. Ninety percent of infections occurred where the daily mean ambient temperatures were below 10oC; where daily average global radiation exceeded 500kJ/m2/hour; where sunshine was less than 5 hours per day; or where relative humidity was above 80%. Coronavirus infections were significantly more common where daily average global radiation was under 300 kJ/m2/hour (OR 4.3; CI 3.9-4.6; p<0.001); where average relative humidity was over 84% (OR 1.9; CI 3.9-4.6; p<0.001); where average air temperature was below 10oC (OR 6.7; CI 6.1-7.3; p<0.001) or where sunshine was below 4 hours (OR 2.4; CI 2.2-2.6; p<0.001) when compared to the distribution of weather values for the same time period. Seasonal coronavirus infections in children under three years old were more frequent at the start of an annual epidemic than at the end, suggesting that the size of the susceptible child population may be important in the annual cycle. Conclusions: The dynamics of seasonal coronaviruses reflect immunological, weather, social and travel drivers of infection. Evidence from studies on different coronaviruses suggest that low temperature and low radiation/sunlight favour survival. This implies a seasonal increase in SARS-CoV-2 may occur in the UK and countries with a similar climate as a result of an increase in the R0 associated with reduced temperatures and solar radiation. Increased measures to reduce transmission will need to be introduced in winter months for COVID-19.

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“…1,2 While the burden of influenza viruses is best studied, non-influenza viruses such as respiratory syncytial virus (RSV), human metapneumovirus (hMPV), human coronaviruses (CoV), adenoviruses (AV), and parainfluenza viruses (PIV) are responsible for a substantial burden of illness in adults. [3][4][5][6] However, the population-based incidence and burden of community-onset non-influenza respiratory viruses associated with hospitalization in adults have not been systematically assessed. Previous approaches have utilized weekly laboratory surveillance and syndromic surveillance associated with discharge data in statistical models to estimate rates of hospitalization and mortality associated with respiratory viruses.…”

Section: Backg Rou N Dmentioning

confidence: 99%

Comparative incidence and burden of respiratory viruses associated with hospitalization in adults in New York City

Sieling

Goldman

Oberhardt

et al. 2021

Influenza Resp Viruses

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Background Although the burden of influenza is well characterized, the burden of community‐onset non‐influenza respiratory viruses has not been systematically assessed. Understanding the severity and seasonality of non‐influenza viruses, including human coronaviruses, will provide a better understanding of the overall disease burden from respiratory viruses that could better inform resource utilization for hospitals and highlight the value of preventative strategies, including vaccines. Methods From October 2017 to September 2019, a retrospective study was performed in a pre‐defined catchment area to estimate the population‐based incidence of community‐onset respiratory viruses associated with hospitalization. Included patients were ≥18 years old, resided in New York City, were hospitalized for ≥24 hours, and had a respiratory virus detected within 3 calendar‐days of admission. Disease burden was measured by hospital length of stay (LOS), intensive care unit (ICU) admissions, and in‐hospital mortality and compared among those with laboratory‐confirmed influenza versus those with laboratory‐confirmed non‐influenza viruses (human coronaviruses, parainfluenza viruses, respiratory syncytial virus, human metapneumovirus, and adenovirus). Results During the study period, 4232 eligible patients were identified of whom 50.9% were ≥65 years of age. For each virus, the population‐based incidence was highest for those ≥80 years of age. When compared to those with influenza viruses detected, those with non‐influenza respiratory viruses detected (combined) had higher population‐based incidence, significantly more ICU admissions, and higher in‐house mortality. Conclusions The burden of non‐influenza respiratory viruses for hospitalized adults is substantial. Prevention and treatment strategies are needed for non‐influenza respiratory viruses, particularly for older adults.

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Clinical Features, Epidemiology, and Climatic Impact of Genotype-specific Human Metapneumovirus Infections: Long-term Surveillance of Hospitalized Patients in South Korea

Cited by 22 publications

References 29 publications

The impact of environmental variables on the spread of COVID-19 in the Republic of Korea

The impact of environmental variables on the spread of COVID-19 in the Republic of Korea

Coronavirus Seasonality, Respiratory Infections and Weather

Comparative incidence and burden of respiratory viruses associated with hospitalization in adults in New York City

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