Clinical Features and Prognosis in Ocular Toxoplasmosis

Abstract

Ocular toxoplasmosis commonly affects the macula and seriously impairs visual acuity. The prevention of acquired and congenital infections is very important in controlling ocular toxoplasmosis. Patients should be followed to avoid late complications.

Incidence and clinical characteristics in a Colombian cohort of ocular toxoplasmosis

“…9 There was no difference in gender distribution of the disease, and the age of presentation was similar to that reported in other series 10,11 but the 37% of definitive unilateral blindness is higher than the 24% reported in the Netherlands. 10 Primary lesions were less frequent than recurrent lesions in a similar manner to previous case series.…”

“…Many characteristics of the lesions are similar to those previously reported 10,11,13 with a predominance of macular localization. Papillitis has been described as an atypical presentation in ocular toxoplasmosis; we found this in 7% of cases, which is near to the 5% reported in Turkey.…”

“…10 Primary lesions were less frequent than recurrent lesions in a similar manner to previous case series. 10,11 The frequency of 17% of a positive IgM assay was lower than that reported previously of 47% for patients during the acute phase of ocular toxoplasmosis in the same region in Colombia by the high-sensitive assay ISAGA and of 37% in Iran. 12,13 This could be partly explained by the different commercial assays used.…”

“…Papillitis has been described as an atypical presentation in ocular toxoplasmosis; we found this in 7% of cases, which is near to the 5% reported in Turkey. 11 There were six patients with chorioretinitis without frank vitritis (18%), which could be explained by a low inflammatory reaction in these cases. There are no available data in the literature to determine whether our patients have a different number or size of lesions relative to other geographical regions; however, we did not observe differences between acquired and the congenital presentation.…”

“…In 89 eyes (six eyes were lost to follow-up and they were seen only during the period of vitritis), the median number of lesions was two (range: [1][2][3][4][5][6][7][8][9][10][11]. No difference in the number of lesions was found between congenital or acquired infections (mean: 1.8±1.6 vs 1.8±1.5).…”