Clinical Features and Prognosis in Ocular Toxoplasmosis

Abstract

Ocular toxoplasmosis commonly affects the macula and seriously impairs visual acuity. The prevention of acquired and congenital infections is very important in controlling ocular toxoplasmosis. Patients should be followed to avoid late complications.

Active ocular toxoplasmosis in Turkish patients: a report on 109 cases

“…The data presented here confirm the characteristic clinical features of OT: central lesions are more common than peripheral lesions, recurrences are more common in eyes that have preexisting scars than previously uninvolved eyes, active lesions frequently arise from retinochoroidal scars and are typically single and smaller than two disc diameters in immunocompetent patients [7,8,10,16,23]. The close association of active lesions with preexisting scars, especially with those of the most recent episode may support the hypotheses that organisms spread into the surrounding retina during activations and that more viable tissue cysts are more likely to cause subsequent activations [1].…”

“…The demographic features of our patients are similar to those reported in other large series [7,8]. There was no gender predilection and most of the patients were younger than 35 years.…”

Active ocular toxoplasmosis in Turkish patients: a report on 109 cases

“…The data presented here confirm the characteristic clinical features of OT: central lesions are more common than peripheral lesions, recurrences are more common in eyes that have preexisting scars than previously uninvolved eyes, active lesions frequently arise from retinochoroidal scars and are typically single and smaller than two disc diameters in immunocompetent patients [7,8,10,16,23]. The close association of active lesions with preexisting scars, especially with those of the most recent episode may support the hypotheses that organisms spread into the surrounding retina during activations and that more viable tissue cysts are more likely to cause subsequent activations [1].…”

“…The demographic features of our patients are similar to those reported in other large series [7,8]. There was no gender predilection and most of the patients were younger than 35 years.…”

Challenging Diagnosis of Atypical Toxoplasmic Neuroretinitis in Children: A Case Series

“…This is based on literature that state that the etiology of NR due to toxoplasmosis can be made clear by the presence of serum IgM antibodies, or by the fourfold rise in IgG. Our results also show acute infection [2,22,23] and is supported by the statement that IgG antibodies appear within the first 2 weeks after infection [24]. Ronday et al [25] suggested that an IgG titer of more than 300 IU is indicative of acute infection.…”

Incidence and clinical characteristics in a Colombian cohort of ocular toxoplasmosis

“…9 There was no difference in gender distribution of the disease, and the age of presentation was similar to that reported in other series 10,11 but the 37% of definitive unilateral blindness is higher than the 24% reported in the Netherlands. 10 Primary lesions were less frequent than recurrent lesions in a similar manner to previous case series.…”

“…Many characteristics of the lesions are similar to those previously reported 10,11,13 with a predominance of macular localization. Papillitis has been described as an atypical presentation in ocular toxoplasmosis; we found this in 7% of cases, which is near to the 5% reported in Turkey.…”

Active ocular toxoplasmosis in Turkish patients: a report on 109 cases

“…The data presented here confirm the characteristic clinical features of OT: central lesions are more common than peripheral lesions, recurrences are more common in eyes that have preexisting scars than previously uninvolved eyes, active lesions frequently arise from retinochoroidal scars and are typically single and smaller than two disc diameters in immunocompetent patients [7,8,10,16,23]. The close association of active lesions with preexisting scars, especially with those of the most recent episode may support the hypotheses that organisms spread into the surrounding retina during activations and that more viable tissue cysts are more likely to cause subsequent activations [1].…”

“…The demographic features of our patients are similar to those reported in other large series [7,8]. There was no gender predilection and most of the patients were younger than 35 years.…”

Challenging Diagnosis of Atypical Toxoplasmic Neuroretinitis in Children: A Case Series

“…This is based on literature that state that the etiology of NR due to toxoplasmosis can be made clear by the presence of serum IgM antibodies, or by the fourfold rise in IgG. Our results also show acute infection [2,22,23] and is supported by the statement that IgG antibodies appear within the first 2 weeks after infection [24]. Ronday et al [25] suggested that an IgG titer of more than 300 IU is indicative of acute infection.…”

Incidence and clinical characteristics in a Colombian cohort of ocular toxoplasmosis

“…9 There was no difference in gender distribution of the disease, and the age of presentation was similar to that reported in other series 10,11 but the 37% of definitive unilateral blindness is higher than the 24% reported in the Netherlands. 10 Primary lesions were less frequent than recurrent lesions in a similar manner to previous case series.…”

“…Many characteristics of the lesions are similar to those previously reported 10,11,13 with a predominance of macular localization. Papillitis has been described as an atypical presentation in ocular toxoplasmosis; we found this in 7% of cases, which is near to the 5% reported in Turkey.…”

Active ocular toxoplasmosis in Turkish patients: a report on 109 cases

“…The data presented here confirm the characteristic clinical features of OT: central lesions are more common than peripheral lesions, recurrences are more common in eyes that have preexisting scars than previously uninvolved eyes, active lesions frequently arise from retinochoroidal scars and are typically single and smaller than two disc diameters in immunocompetent patients [7,8,10,16,23]. The close association of active lesions with preexisting scars, especially with those of the most recent episode may support the hypotheses that organisms spread into the surrounding retina during activations and that more viable tissue cysts are more likely to cause subsequent activations [1].…”

“…The demographic features of our patients are similar to those reported in other large series [7,8]. There was no gender predilection and most of the patients were younger than 35 years.…”

Challenging Diagnosis of Atypical Toxoplasmic Neuroretinitis in Children: A Case Series

“…This is based on literature that state that the etiology of NR due to toxoplasmosis can be made clear by the presence of serum IgM antibodies, or by the fourfold rise in IgG. Our results also show acute infection [2,22,23] and is supported by the statement that IgG antibodies appear within the first 2 weeks after infection [24]. Ronday et al [25] suggested that an IgG titer of more than 300 IU is indicative of acute infection.…”

Incidence and clinical characteristics in a Colombian cohort of ocular toxoplasmosis

“…9 There was no difference in gender distribution of the disease, and the age of presentation was similar to that reported in other series 10,11 but the 37% of definitive unilateral blindness is higher than the 24% reported in the Netherlands. 10 Primary lesions were less frequent than recurrent lesions in a similar manner to previous case series.…”

“…Many characteristics of the lesions are similar to those previously reported 10,11,13 with a predominance of macular localization. Papillitis has been described as an atypical presentation in ocular toxoplasmosis; we found this in 7% of cases, which is near to the 5% reported in Turkey.…”