Clinical features and nail clippings in 52 children with psoriasis

Abstract

There seems to be a correlation between some microscopic nail features in children with psoriasis and their PASI and NAPSI scores, so nail clippings from children with suspected psoriasis may help with diagnosis, especially in the presence of neutrophils, and in excluding onychomycosis.

Clinical and histological spectrum of nail psoriasis: A cross‐sectional study

“…Recently, the use of nail clipping microscopy as a diagnostic tool for nail psoriasis has also been studied . Although there are many studies delineating the clinical features of nail psoriasis, very few have described the histopathological features, or tried to correlate the two.…”

“…[8][9][10][11] Recently, the use of nail clipping microscopy as a diagnostic tool for nail psoriasis has also been studied. [12][13][14][15] Although there are many studies delineating the clinical features of nail psoriasis, very few have described the histopathological features, or tried to correlate the two. In an attempt to bridge this gap, this descriptive cross-sectional study was undertaken to study the histopathological features of nail psoriasis.…”

“…Comparative table with frequency of histopathological features8,9,12,14,15 PAS stain refers to the periodic acid-Schiff stain performed on tissue specimen to evaluate the presence of fungal elements. In the studies included here, both H&E and PAS stain were performed in all cases with two exceptions: Uber et al used only PAS stain with diastase in their study and Hanno et al stained only with H&E. The percentage of positive cases indicates the number of cases with presence of either hyphae, yeast forms or spores in the nail tissue.…”

Liquid chromatography–tandem mass spectrometry is effective for analysis of ergosterol in fungal‐infected nails

“…Onychomycosis is classified into five different types depending on the invaded location: distal lateral subungual, white superficial, proximal subungual, endonyx and total dystrophic. Uber et al . suggested that the presence of nondermatophyte onychomycosis in patients with psoriasis is combined with pitting and salmon patches on the nail.…”

“…Onychomycosis is classified into five different types depending on the invaded location: distal lateral subungual, white superficial, proximal subungual, endonyx and total dystrophic. Uber et al 9 suggested that the presence of nondermatophyte onychomycosis in patients with psoriasis is combined with pitting and salmon patches on the nail. Having the hands constantly immersed in water can predispose to the development of chronic paronychia, resulting in poor nail growth, 10 infection with Pseudomonas aeruginosa 11 or onycholysis.…”