Clinical features and management of Meniere’s disease patients with drop attacks

Wu, Qianru; Li, Xuanyi; Sha, Yan; Dai, Chenyang

doi:10.1007/s00405-018-5260-5

Cited by 28 publications

(28 citation statements)

References 27 publications

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“…SSD can be congenital, sudden or progressive. The most common causes of SSD in adulthood are sudden and idiopathic, including vestibular schwannoma [2] and associated surgery [3], Ménière's disease [4], and sudden-onset sensorineural hearing loss [5]. The incidence of SSD in the United Kingdom is estimated to be approximately 9000 new cases per year [6].…”

Section: Introductionmentioning

confidence: 99%

Core Rehabilitation Outcome Set for Single Sided Deafness (CROSSSD) study: protocol for an international consensus on outcome measures for single sided deafness interventions using a modified Delphi survey

Katiri

Hall

Buggy

et al. 2020

Trials

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Background: Single-sided deafness (SSD) describes the presence of a unilateral severe to profound sensorineural hearing loss. SSD disrupts spatial hearing and understanding speech in background noise. It has functional, psychological and social consequences. Potential options for rehabilitation include hearing aids and auditory implants. Benefits and harms of these interventions are documented inconsistently in the literature, using a variety of outcomes ranging from tests of speech perception to quality of life questionnaires. It is therefore difficult to compare interventions when rehabilitating SSD. The Core Rehabilitation Outcome Set for Single Sided Deafness (CROSSSD) study is an international initiative that aims to develop a minimum set of core outcomes for use in future trials of SSD interventions. Methods/design: The CROSSSD study adopts an international two-round online modified Delphi survey followed by a stakeholder consensus meeting to identify a patient-centred core outcome domain set for SSD based on what is considered critical and important for assessing whether an intervention for SSD has worked. Discussion: The resulting core outcome domain set will act as a minimum standard for reporting in future clinical trials and could have further applications in guiding the use of outcome measures in clinical practice. Standardisation will facilitate comparison of research findings.

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Section: Introductionmentioning

confidence: 99%

Core Rehabilitation Outcome Set for Single Sided Deafness (CROSSSD) study: protocol for an international consensus on outcome measures for single sided deafness interventions using a modified Delphi survey

Katiri

Hall

Buggy

et al. 2020

Trials

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“…Ménière's disease (MD) is an idiopathic disorder of the inner ear, characterized by vertigo attacks, sensorineural hearing loss, tinnitus, and vegetative symptoms [1]. Management of MD is based on conservative symptomatic treatment of vertigo attacks, prophylactic treatment and lifestyle counselling (e.g.…”

Section: Introductionmentioning

confidence: 99%

Intratympanic gentamycine for Ménière’s disease: is there a selective vestibulotoxic effect?

Molnár

Maihoub

Gáborján

et al. 2020

Eur Arch Otorhinolaryngol

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The aim of our study is to investigate the effectiveness and safety of the treatment, based on vertigo diaries and pure tone audiograms. Methods The complete medical documentation of 105 definite patients suffering from Ménière's disease was analyzed. In the studied group, nine patients were treated with intratympanic gentamycine. Long-term follow-up of the patients was carried out, using vertigo diaries, medical letters, anamnestic data, and pure tone audiograms. Audiometric results and vertigo complaints before and after treatment were contrasted using IBM SPSS V24 software. Results Based on our analysis, vertigo attacks appeared significantly less often after gentamycine treatment [p < 0.001; Odds ratio 0.003 (95% CI 0.001-0.012)], which confirms the efficacy of the therapy. Pure tone stages before and after the application of gentamycine were contrasted using the Mann-Whitney U test. When comparing the audiometric results of long-term follow-ups by using the logistic regression, a statistically significant difference was observed between the treated and not treated groups [p = 0.001; Odds ratio 0.141 (95% CI 0.064-0.313)], and based on the survivorship curve hearing impairment was more common in the not treated group which also supports our results. Based on the non-parametric test, there was no significant difference (p = 0.84) between the pure-tone stages of the control group and of those treated with gentamycine. Conclusion Our results indicate that intratympanic gentamycine is effective in controlling vertigo attacks, and there is no higher risk for hearing loss than in case of spontaneous progression of the disorder.

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“…In their article, Wu et al [1] present clinical data and results from hydrops MR imaging in patients with hydropic ear disease (Menière's) with or without drop attacks. Drop attacks are sudden and unexpected fall/near-fall events due to paroxysmal vestibular dysfunction and loss of postural tone and are associated with serious fall-associated comorbidity.…”

mentioning

confidence: 99%

“…Wu et al [1] found that patients with drop attacks had a higher degree of endolymphatic hydrops than those without drop attacks. Furthermore, they state that "In our previous study [20], we demonstrated that MD patients suffered from gradual deterioration of EH with disease progression (…)".…”

mentioning

confidence: 99%

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Drop attacks, hydrops severity, and disease duration in hydropic ear disease (Menière’s)

Gürkov

2019

Eur Arch Otorhinolaryngol

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Clinical features and management of Meniere’s disease patients with drop attacks

Cited by 28 publications

References 27 publications

Core Rehabilitation Outcome Set for Single Sided Deafness (CROSSSD) study: protocol for an international consensus on outcome measures for single sided deafness interventions using a modified Delphi survey

Core Rehabilitation Outcome Set for Single Sided Deafness (CROSSSD) study: protocol for an international consensus on outcome measures for single sided deafness interventions using a modified Delphi survey

Intratympanic gentamycine for Ménière’s disease: is there a selective vestibulotoxic effect?

Drop attacks, hydrops severity, and disease duration in hydropic ear disease (Menière’s)

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