Clinical features and diagnostic reliability in paediatric laryngopharyngeal reflux

Baudoin, Tomislav; Čor, Ivana Samardžija; Žaja, Orjena

doi:10.1016/j.ijporl.2014.04.024

Cited by 17 publications

(17 citation statements)

References 24 publications

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“…10,11,17,18 The results of our study, as well as those of previously published studies, show that the diagnosis confirmation rate can be improved without subjecting the patient to unnecessary testing. 22 With the help of data gathered in our study, patient symptoms and factors that have been correlated to extra-esophageal symptoms in our patient cohort were used to develop a risk score to reduce unnecessary testing and help administer proper and cost-effective treatment 23 (►Table 1). When allocating the patients into risk groups, four major criteria were used; respiratory symptoms and findings (otorhinolaryngologist evaluation); gastrointestinal symptoms (gastroenterologist evaluation); respiratory comorbidity (asthma or recurrent laryngitis); and presence of obesity.…”

Section: Discussionmentioning

confidence: 99%

Significance of Extra-Esophageal Symptoms in Pediatric Gastroesophageal Reflux Disease

Žaja

Matovinović

Jelavić

et al. 2020

Int Arch Otorhinolaryngol

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Introduction Current practice guidelines in gastroesophageal reflux disease (GERD) often require invasive diagnostic testing. Objective The aim of the present study was to evaluate the significance of extra-esophageal symptoms and reliability of a screening risk score that is simple to use. Methods A longitudinal retrospective single-institution cohort study. Setting: A university clinical hospital tertiary referral center. The present study enrolled pediatric patients with symptoms suggestive of GERD: epigastric pain, occasional nausea, regurgitation, tasting acid in the oral cavity, chronic cough, hoarseness of voice, frequent throat clearing. The patients underwent 24-hour esophageal pH monitoring and fiber-optic laryngoscopy. The correlations between the local findings, anamnestic and objective measurement data were analyzed. Results The present study evaluated 89 pediatric patients. Patients with asthma presented significantly more often with adjoining gastrointestinal symptoms (p = 0.0472). Patients that were obese were linked to a higher rate of reports of gastrointestinal symptoms (p = 0.0495). After the patients had been assigned to newly developed risk groups, obesity showed to be significantly more frequent in patients placed in higher risk groups (p < 0.0001) for a positive GERD diagnosis. Conclusion Patients with leading symptoms of asthma presented significantly more often with adjoining gastrointestinal symptoms. Obesity showed to be significantly more frequent in patients placed in higher risk groups for a positive GERD diagnosis.

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Section: Discussionmentioning

confidence: 99%

Significance of Extra-Esophageal Symptoms in Pediatric Gastroesophageal Reflux Disease

Žaja

Matovinović

Jelavić

et al. 2020

Int Arch Otorhinolaryngol

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“…2 Hyperplastischer Zungengrund einer 4-jährigen LPRD-Patientin (Aufnahme im Rahmen einer Intubationsnarkose zur Paukenröhrcheneinlage). Wahrscheinlichkeit für das Vorhandensein einer kindlichen LPRD anhand der erhobenen endoskopischen Befunde einzuschätzen, kann das PLPR Diagnostic Probability Scoring nach Baudoin hilfreich sein[9]. Neben den vorhandenen Symptomen und endoskopischen Befunden wird zur Ermittlung eines Scores, der das Risiko für das Vorhandensein einer kindlichen LPRD angibt, auch der BMI und das Vorhandensein von Asthma oder einer rezidivierenden Laryngitis miteinbezogen[9].…”

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Laryngopharyngeale Refluxerkrankung (LPRD) bei Kindern

Reichel¹,

Saravakos²,

Lorenz³

2017

Laryngo-Rhino-Otol

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LPRD in children is characterized by symptoms, clinical findings, and sequelae caused by the reflux of gastric acid, bile acid or refluxate containing pepsin beyond the esophagus. For diagnostic procedures and therapy of gastroesophageal reflux disease (GERD) in children and adults widely accepted guidelines have been established. However, diagnosis and therapy of LPRD in children remains a continuous issue of inter- and intradisciplinary discussions. Although both GERD and LPRD in children are reflux-induced diseases, these two entities are different in symptoms, cause, diagnostic procedures, and therapy. Thus, the terms GERD and LPRD are not eligible to be used as synonyms.Otorhinolaryngologists are becoming more and more involved in the management of children with suspicious LPRD. With flexible transnasal laryngopharyngoscopy being one of the most important diagnostic tools for LPRD detection, otorhinolaryngologists play an important role in the interdisciplinary diagnostic network of physicians treating children with suspected LPRD. The present article highlights age-dependent clinical symptoms, diagnostic tools, differential diagnoses, and adequate therapy for pediatric LPRD.

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“…Они же имеют более выраженные клинические проявления болезни по сравнению с девочками [20]. Интересно, что в 46% случаев ла рингофарингеальный рефлюкс может диагностиро ваться у детей с абсолютно нормальными показате лями pHмониторинга пищевода [21].…”

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“…Наблюдается отеч ность задней трети голосовых складок (до 75,8% случаев), реже диффузный отек голосовых складок (50%), гипертрофия слизистой оболочки межчерпа ловидной области -эта зона в зарубежной литера туре больше известна под названием «задняя комис сура» (33,8%). Крайне редко встречается отек под складочного отдела гортани -4,8% [20,22].…”

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“…Четких диагностических алгорит мов в настоящее время не существует [12]. Большин ство авторов рекомендуют суточный рНмони торинг, в частности с введением дополнительного зонда в носоглотку [20,29,[50][51][52][53]. Однако изза научные ОБзОры сложности манипуляции и возможных психологи ческих моментов этот метод у детей не считается аб солютно необходимым при явных клинических про явлениях ЭЭР со стороны ЛОРорганов [37,47].…”

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Extraesophageal reflux in children (A review of literature)

Shilenkova¹

2015

Ross. rinol.

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Ключевые слова: экстраэзофагеальный рефлюкс, детский возраст.objective: to systemize the data available in the literature on extraesophageal reflux in children and its significance in the development of chronic diseases of the upper respiratory tract and ear. the review highlights the basic problems of the pathogenesis, diagnosis, and clinic presentations of the extraesophageal manifestations of gastroesophageal reflux disease. It analyzes the expediency of antireflux therapy in revealing the association of Ent diseases with gastroesophageal reflux.

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Clinical features and diagnostic reliability in paediatric laryngopharyngeal reflux

Cited by 17 publications

References 24 publications

Significance of Extra-Esophageal Symptoms in Pediatric Gastroesophageal Reflux Disease

Significance of Extra-Esophageal Symptoms in Pediatric Gastroesophageal Reflux Disease

Laryngopharyngeale Refluxerkrankung (LPRD) bei Kindern

Extraesophageal reflux in children (A review of literature)

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