Clinical Features and Course of Ankylosing Spondylitis: As seen in a Follow-up of 222 Hospital Referred Cases

Wilkinson, Mark; Bywaters, E. G. L.

doi:10.1136/ard.17.2.209

Cited by 275 publications

(66 citation statements)

References 11 publications

(3 reference statements)

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“…There have been many publications in the literature on the occurrence of spinal or spinal cord injury in AS patients (Guttmann, 1966;Hollin et al, 1965;Hunter and Dubo, 1983;Kewalramani et al, 1975;Murray and Persellin, 1981;Wein stein et al, 1982;Wilkinson and Bywaters, 1958;Woodruff and Dewing, 1963). However, few authors described its incidence in these patients.…”

Section: Discussionmentioning

confidence: 99%

“…In a review of 2,500 patients with spinal injury Guttmann (1966) found only seven with AS and five of his seven patients had traumatic tetraplegia. Wilkinson and Bywaters (1958) noted two patients with lumbar fracture in a review of 222 AS patients who were followed for from one to 20 years (mean, 4.6 years). Weinstein et al (1982), in their study of 105 consecutive cases of AS, noticed that the frequency of spinal fracture was 12 per cent and the frequency of myelopathy was 8 per cent.…”

Section: Discussionmentioning

confidence: 99%

“…However, spinal fractures associated with AS are un common (Kewalramani et al, 1975;Wilkinson and Bywaters, 1958). When a complete fracture does occur it is very unstable and is associated with a high risk of neurological deterioration (Hunter and Dubo, 1978;Kewalramani et al, 1975).…”

Section: Introductionmentioning

confidence: 99%

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Cervical spinal cord injury complicating ankylosing spondylitis

1985

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SummaryWithin a period of 12 years 466 patients with acute spinal cord injury were admitted to our Centre, seven of these having ankylosing spondylitis (AS), A history of alcohol consumption preceding the accident was present in five patients, and in four there was a history of neurological deterioration before their admission. An epidural hematoma was found in one patient and four expired within 3 months of their injury,The incidence of ankylosing spondylitis in cervical cord injury was 1.5°,,, and an associated epidural hematoma was present in some 14% of the patients, The mortality rate was 57%, There was a high incidence of alcoholic use before the accident. Neurological deterioration commonly occurred before admission,

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Cervical spinal cord injury complicating ankylosing spondylitis

1985

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“…Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disorder known as spondyloarthropathies [1] that primarily affects the spine and axial joints, causing pain, stiffness and a progressive thoracolumbar kyphotic deformity [2]. In the untreated cases, the long-lasting persistent inflammation causes progressive rigidity of the entire spine which could subsequently lead to two major complications of AS: the hyperkyphosis of thoracolumbar spine and neurological complications [2].…”

Section: Introductionmentioning

confidence: 99%

“…In the untreated cases, the long-lasting persistent inflammation causes progressive rigidity of the entire spine which could subsequently lead to two major complications of AS: the hyperkyphosis of thoracolumbar spine and neurological complications [2]. Lumbosacral radiculopathies, cauda equine syndrome and compression of the spinal cord have been reported as extra-articular manifestations of AS [3,4].…”

Section: Introductionmentioning

confidence: 99%

Thoracic spinal cord herniation in a patient with long-standing ankylosing spondylitis

et al. 2010

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The objective of this study was to describe an adult male patient with ankylosing spondylitis (AS) associated with thoracic spinal cord herniation (TSCH). TSCH is a scarce entity presented as a displacement of thoracic cord through an anterior or anterolateral dural defect. More importantly, the co-occurrence of AS and thoracic spinal cord herniation is exceptional. To date, only one case of SCH in association with AS has been reported in the literature. A 56-year-old male patient presented with the progressive difficulty in walking and numbness of both lower limbs for the past 18 months. The patient was diagnosed as AS when he was 30 years old. Sagittal MRI of thoracic spine showed dural defect of the posterior aspect of T11 and 12 vertebral bodies. Axial T2-weighted MRI demonstrated that spinal cord was displaced ventrally and to the right. The diagnosis of TSCH with AS was established. The prognosis was explained to the patient. We recommended duraplasty for dural repair to the patient, but he refused surgery. The results demonstrated that TSCH associated with long-standing AS was very uncommon, and MRI is recommended to rule out SCH in the long-standing AS patients with neurologic symptoms. The SCH in AS might be caused by inflammation, and thoracolumbar hyperkyphosis results from AS might be associated with the development of SCH.

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Arthritis With Nodules Following Ankylosing Spondylitis

Rosenthal¹

1968

JAMA

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Clinical Features and Course of Ankylosing Spondylitis: As seen in a Follow-up of 222 Hospital Referred Cases

Cited by 275 publications

References 11 publications

Cervical spinal cord injury complicating ankylosing spondylitis

Cervical spinal cord injury complicating ankylosing spondylitis

Thoracic spinal cord herniation in a patient with long-standing ankylosing spondylitis

Arthritis With Nodules Following Ankylosing Spondylitis

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