Clinical features and anaphylaxis in children with cold urticaria

Alangari, Abdullah; Twarog, Frank J.; Shih, Mei‐Chiung; Schneider, Lynda C.

doi:10.1016/s0091-6749(03)80830-8

Cited by 18 publications

(41 citation statements)

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“…Extensive cold contact, e.g., diving in cold water, may provoke systemic symptoms such as dyspnea, hypotension, and loss of consciousness in addition to wheals resembling anaphylaxis and may lead to death [15]. A retrospective study revealed a mean temperature threshold of 13.7 ± 6.0 °C; range 26-4 °C ( Fig.…”

Section: Acquired Cold Urticariamentioning

confidence: 99%

Urticaria and Angioedema: an Update on Classification and Pathogenesis

Radonjic-Hoesli

Scherer

Micaletto

et al. 2017

Clinic Rev Allerg Immunol

114

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Urticaria is a common, mast cell-driven disease presenting with wheals or angioedema or both. In the last years, urticaria has increasingly attracted notice to clinicians and researchers, last but not least inspired by the approval of omalizumab, an anti-IgE antibody, for urticaria treatment. There is wide consensus on the clinical classification based on duration and elicitation. However, the pathogenesis is incompletely understood. This review summarizes current guidelines for the management and novel insights in the pathogenesis of urticaria with special focus on their impact on clinical praxis. The classification of urticaria subgroups is mainly based on clinical criteria: acute and chronic urticaria (CU). Chronic urticaria comprises both chronic spontaneous urticaria (CSU) and chronic inducible urticaria (CIndU) that includes physical and non-physical urticarias. Recent research focused on characterizing the role of cells and mediators involved in the pathogenesis of urticaria, identifying the mechanisms of mast cell activation, and investigating underlying autoimmune processes in chronic spontaneous urticarial. Currently, non-sedating antihistamines and omalizumab, an antiimmunoglobulin E antibody, are recommended for the therapy of chronic urticaria, as both exhibit a favorable efficacy and safety profile. Novel therapeutic strategies aim at specifically targeting cells and mediators involved in the pathogenesis of urticaria.

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Section: Acquired Cold Urticariamentioning

confidence: 99%

Urticaria and Angioedema: an Update on Classification and Pathogenesis

Radonjic-Hoesli

Scherer

Micaletto

et al. 2017

Clinic Rev Allerg Immunol

114

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“…Consequently, many patients are advised to carry an epinephrine autoinjector. 57,58 Cold tolerance induction can be achieved by gradually decreasing the temperature of showers, starting from above the CTT of the patient. 59 Tolerance is then maintained with daily cold showers.…”

Section: Acquired Cold Urticariamentioning

confidence: 99%

Management and treatment of chronic urticaria (CU)

Maurer

Church

Gonçalo

et al. 2015

Acad Dermatol Venereol

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Developments increasing our understanding of chronic urticaria have resulted in the simplification and improvement of available treatments. Currently, many treatments target mast cell mediators, but we can now disrupt mast cell activation with the anti-IgE antibody omalizumab, which has markedly advanced the treatment landscape for patients with difficultto-treat urticaria. Current guidelines provide a framework for the management and treatment of patients with CU but, as each patient is different, knowledge and experience of specialist dermatologists and allergists are key to effective pharmacotherapy. This article reviews the different therapeutic options for patients with chronic spontaneous urticaria (also called chronic idiopathic urticaria) or chronic inducible urticaria and discusses management of special populations or special circumstances related to CU.

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“…If triggers are found, then avoidance advice would be key as well as safety advice, for example, not to enter cold water alone in those with cold-induced urticaria. Since approximately one-third of children with cold-induced urticaria will exhibit features suggestive of anaphylaxis15 then prescription of an appropriate epinephrine autoinjector and training in its use may be necessary. Cold-induced anaphylaxis is more likely in those children experiencing oropharyngeal symptoms with cold food or drinks.…”

Section: Managementmentioning

confidence: 99%

Fifteen-minute consultation: Assessing the child with persistent urticaria

Hardman

Minshall

2019

Arch Dis Child Educ Pract Ed

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Chronic urticaria is the presence of wheals and/or angioedema, with daily or intermittent symptoms lasting more than 6 weeks. Although rarely life threatening, it can be a cause of significant embarrassment and misery. In most cases, no underlying factor is identified. It is therefore important to have a structured approach to the assessment in order to exclude important diagnoses, minimise costly screening tests and ensure a correct diagnosis is made. This article aims to highlight the importance of a focused history, provides a clear scheme for establishing a diagnosis and recommends when to perform appropriate investigations. A short discussion regarding treatment options and prognosis is also provided.

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Clinical features and anaphylaxis in children with cold urticaria

Cited by 18 publications

References 0 publications

Urticaria and Angioedema: an Update on Classification and Pathogenesis

Urticaria and Angioedema: an Update on Classification and Pathogenesis

Management and treatment of chronic urticaria (CU)

Fifteen-minute consultation: Assessing the child with persistent urticaria

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