Clinical feasibility of radiofrequency ablation using novel adjustable separable electrodes with a multipurpose needle for treating small hepatocellular carcinomas: a prospective single center study

Kim, Se Woo; Lee, Jeong Min; Kim, Jae Hyun; Park, Sae-Jin; Yoon, Jeong Hee; Joo, Ijin

doi:10.1080/02656736.2023.2235102

Cited by 1 publication

(1 citation statement)

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“…According to the data provided by the World Health Organization (WHO), hepatocellular carcinoma (HCC) is the world’s sixth most common malignant tumor and the third leading cause of cancer death worldwide in 2020 ( 1 ). It is characterized by a short duration of illness and is difficult to heal, and the invasion, metastasis, and spread of HCC cells are the reasons for the high mortality rate of this disease ( 2 ). The conventional treatment of HCC is still mainly surgical resection, supplemented by drug therapy, but the disadvantage of surgical treatment of HCC is its high risk and challenging nature ( 3 ).…”

Section: Introductionmentioning

confidence: 99%

Antitumor immunostimulatory activity of the traditional Chinese medicine polysaccharide on hepatocellular carcinoma

Liu,

Wu,

Hao

2024

Front. Immunol.

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Hepatocellular carcinoma (HCC) is a prevalent malignancy, often associated with compromised immune function in affected patients. This can be attributed to the secretion of specific factors by liver cancer cells, which hinder the immune response and lead to a state of immune suppression. Polysaccharides derived from traditional Chinese medicine (TCM) are valuable constituents known for their immunomodulatory properties. This review aims to look into the immunomodulatory effects of TCM polysaccharides on HCC. The immunomodulatory effects of TCM polysaccharides are primarily manifested through the activation of effector T lymphocytes, dendritic cells, NK cells, and macrophages against hepatocellular carcinoma (HCC) both in vivo and in vitro settings. Furthermore, TCM polysaccharides have demonstrated remarkable adjuvant antitumor immunomodulatory effects on HCC in clinical settings. Therefore, the utilization of TCM polysaccharides holds promising potential for the development of novel therapeutic agents or adjuvants with advantageous immunomodulatory properties for HCC.

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Section: Introductionmentioning

confidence: 99%