“…As in the previous 5 years [1,2,3,4,5], I am presenting my subjective selection, this time of 16 (primary) articles - actually their summaries - published in the previous year (2015) that I believe may provide some information to help the reader improve his/her clinical practice. As I noted before, the idea was originally proposed by Giovanni Fava [6] with the goal of selecting papers that I would subjectively perceive as having a high ‘Clinical Factor' - the degree and extent to which a journal article provides information to the clinician that may improve his/her practice .…”