Clinical Experiences With Autologous Osteochondral Mosaicplasty in an Athletic Population

Hangody, László; Dobos, Jozsef; Baló, Eszter; Pánics, Gergely; Berkes, István

doi:10.1177/0363546509360405

Cited by 308 publications

(281 citation statements)

References 38 publications

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“…However, this technique possesses many inherent limitations including donor site morbidity, limited quantity of suitable host tissue as well as the difficulty in correctly matching the topography of the graft with the healthy tissue surrounding the defect site [5]. Issues including incomplete integration between the host tissue and graft tissue [6] and the degradation of the graft tissue are often observed [7]. Tissue Engineering (TE) strategies may provide significant advantages compared to these more traditional clinical treatment methods.…”

Section: Introductionmentioning

confidence: 99%

A biomimetic multi-layered collagen-based scaffold for osteochondral repair

et al. 2014

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Section: Introductionmentioning

confidence: 99%

A biomimetic multi-layered collagen-based scaffold for osteochondral repair

et al. 2014

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“…Based on clinical experience in over 1000 MP patients, this technique has become a proven useful alternative for the treatment of 1.0-to 4-cm 2 focal chondral and osteochondral lesions in competitive human athletes (Hangody et al, 2008;Hangody et al, 2010). Clinical experience in the stifle (Bodó et al, 2000;Bodó et al, 2004) and hock (Janicek et al, 2010) joint of horses showed a favourable clinical outcome in all cases.…”

mentioning

confidence: 99%

Mosaic arthroplasty of the medial femoral condyle in horses — An experimental study

Bodó¹,

Vásárhelyi

Hangody

et al. 2014

Acta Veterinaria Hungarica

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One Arabian and 5 Hungarian half-bred horses were used to study the macroscopic and microscopic survival of autologous osteochondral grafts in the weight-bearing surface of the medial femoral condyle (MFC). Grafts were harvested from the cranial surface of the medial femoral trochlea (MFT) under arthroscopic control. Three of them were transplanted into the weight-bearing surface of the contralateral MFC using an arthrotomy approach. Three months later this transplantation procedure was repeated on the opposite stifle joints in the same animals, but at that time transplantation was performed arthroscopically. Follow-up arthroscopy was carried out 12 months after the first operations, and biopsies were taken from both the recipient and the donor sites for histological examination. During follow-up arthroscopy, the transplanted areas looked congruent and smooth. Microscopically, the characteristics of hyaline cartilage were present in 5 out of the 10 biopsies examined; however, in the other half of biopsies glycosaminoglycan (GAG) loss and change in the architecture of the transplanted cartilage was observed. In a 16-year-old horse, all grafts broke during harvesting, and thus transplantation was not performed. No radiological signs of osteoarthritic changes were detected 9 to 12 months after the operations in the donor and recipient joints. Clinically, no lameness or effusion was present three months after the transplantations.

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“…Several studies have reported good clinical outcomes following AOT at both short-and mid-term follow-up [10,57,58]. A recent case series of 85 patients who underwent AOT found improved Foot and Ankle Outcome Score (FAOS) at mean 47.2 months of follow-up and MOCART scores postoperatively at mean 24.8 months of follow-up [59].…”

Section: Replacement Procedures Autologous Osteochondral Transplantationmentioning

confidence: 99%

Osteochondral lesions of the talus in the athlete: up to date review

Shimozono

Yasui

Ross

et al. 2017

Curr Rev Musculoskelet Med

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Purpose of review Osteochondral lesions of the talus (OLT) are common injuries in athletes. The purpose of this study is to comprehensively review the clinical results and return to sport capacity in athletes following treatment for OLT. Recent findings Reparative procedures, such as bone marrow stimulation, and replacement procedures, such as autologous osteochondral transplantation, provide good clinical outcomes in short-and mid-term follow-up in the athlete. Recently, biological augmentation and scaffold-based therapies have been shown to improve clinical and radiological outcomes in OLT in both the general population and athletes. Summary Most studies are of a low level of evidence. Studies analyzing the return to sport capability in athletes are further lacking. High-level evidence and well-designed clinical trials are required to establish the most effective treatment protocol.

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Clinical Experiences With Autologous Osteochondral Mosaicplasty in an Athletic Population

Cited by 308 publications

References 38 publications

A biomimetic multi-layered collagen-based scaffold for osteochondral repair

A biomimetic multi-layered collagen-based scaffold for osteochondral repair

Mosaic arthroplasty of the medial femoral condyle in horses — An experimental study

Osteochondral lesions of the talus in the athlete: up to date review

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