Clinical experience with portable cardiopulmonary bypass in cardiac arrest patients

Hartz, Renée S.; LoCicero, Joseph; Sanders, John H.; Frederiksen, James W.; Joob, Axel W.; Michaelis, Lawrence L.

doi:10.1016/0003-4975(90)90490-w

Cited by 72 publications

(16 citation statements)

References 10 publications

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“…In spite of successful hemodynamic resuscitation, there were no long-term survivors (26). A similar experience showed no survivors among 29 cardiac arrest patients placed on portable CPB when the cardiac pathology was not corrected (27). This recovery is surprising in light of the perception that irreversible damage follows 4 minutes of arrest, and illustrates the effective use of CPB in maintaining cerebral blood flow.…”

Section: Cpb Support During Arrestmentioning

confidence: 96%

Sudden cardiac death: Directing the scope of resuscitation towards the heart and brain

Athanasuleas

Allen²,

Beyersdorf³

et al. 2006

Resuscitation

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Section: Cpb Support During Arrestmentioning

confidence: 96%

Sudden cardiac death: Directing the scope of resuscitation towards the heart and brain

Athanasuleas

Allen²,

Beyersdorf³

et al. 2006

Resuscitation

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“…The difference in outcome between IHCA and OHCA results more from the duration of cardiac arrest than from the location of cardiac arrest itself (Tables 1-3) [43][44][45][46][47][48][49][50][51][52][53][54][55][56][57]. The difference in outcome between IHCA and OHCA results more from the duration of cardiac arrest than from the location of cardiac arrest itself (Tables 1-3) [43][44][45][46][47][48][49][50][51][52][53][54][55][56][57].…”

Section: Extracorporeal Membrane Oxygenation For Out-of-hospital Cardmentioning

confidence: 99%

Extracorporeal cardiopulmonary resuscitation

Fagnoul

Combes

Backer

2014

Current Opinion in Critical Care

127

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This review highlights that ECPR is feasible for both IHCA and OHCA. In the recent series, the outcome of ECPR in IHCA is satisfactory, with survival rates good with neurologic outcome reaching the 40-50% range. All series converge in highlighting that time from cardiac arrest to ECMO flow is a critical determinant of outcome, with survival rates of 50% when initiated within 30 min of IHCA, 30% between 30 and 60 min, and 18% after 60 min. Results of ECPR in OHCA are more challenging. Recent series suggest that good outcome can be obtained in 15-20% of the patients, provided that time from arrest to ECMO is shorter than 60 min. Duration of cardiac arrest seems to be more important than location of cardiac arrest. ECPR thus seems to be a valuable option in selected cases.

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“…Although minimal delay in CPR may exist in hospitals with trained teams, implementation of CPB requires a 10-to 15-minute period of CPR-ALS to allow for rapid surgical or percutaneous access of femoral vessels [18,19]. A recent systematic review of 54 trials emphasizes the value of emergency CPB for treatment of CA [6].…”

Section: Commentmentioning

confidence: 99%

Resuscitation After Prolonged Cardiac Arrest: Role of Cardiopulmonary Bypass and Systemic Hyperkalemia

Liakopoulos

Allen

Hristov

et al. 2010

The Annals of Thoracic Surgery

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Background. The purpose of this study was to determine (1) the role of emergency cardiopulmonary bypass (CPB) after prolonged cardiac arrest and failed cardiopulmonary resuscitation, and (2) the use of systemic hyperkalemia during CPB to convert intractable ventricular fibrillation (VF).Methods. Thirty-one pigs (34 ؎ 2 kg) underwent 15 minutes of cardiac arrest after induced VF, followed by 10 minutes of cardiopulmonary resuscitation-advanced life support. Peripheral CPB was used if cardiopulmonary resuscitation failed to restore stable circulation. Damage was assessed by evaluating hemodynamics, biochemical variables (creatine kinase-MB, neuron-specific enolase), neurologic deficit score, and brain magnetic resonance imaging.Results. Cardiopulmonary resuscitation alone was successful in only 19% (6 of 31 pigs). Cardiopulmonary bypass was initiated in 81% of animals (25 of 31 pigs) either for hypotension (5 of 25 pigs) or intractable VF (20 of 25 pigs). Defibrillation was successful in 7 of 20 animals during the first 10 minutes after initiating CPB.

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Clinical experience with portable cardiopulmonary bypass in cardiac arrest patients

Cited by 72 publications

References 10 publications

Sudden cardiac death: Directing the scope of resuscitation towards the heart and brain

Sudden cardiac death: Directing the scope of resuscitation towards the heart and brain

Extracorporeal cardiopulmonary resuscitation

Resuscitation After Prolonged Cardiac Arrest: Role of Cardiopulmonary Bypass and Systemic Hyperkalemia

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