Clinical experience with patients with olfactory complaints, and their quality of life

Brämerson, Annika; Nordin, Steven; Bende, Mats

doi:10.1080/00016480600801357

Cited by 115 publications

(104 citation statements)

References 20 publications

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“…Normal olfactory function is not only important for protective purposes (eg, detecting spoiled foods or occupational hazards), but it is an important aspect of social, functional, and emotional well-being. As a result, olfactory dysfunction has been shown to reduce overall quality of life [29]. A recent study by Litvack et al [28] evaluated HRQoL in patients with CRS and olfactory dysfunction.…”

Section: Olfactory Dysfunction In Chronic Rhinosinusitismentioning

confidence: 98%

Quality of Life in Patients with Chronic Rhinosinusitis

Rudmik

Smith

2011

Curr Allergy Asthma Rep

154

136

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Health-related quality of life (HRQoL) is a domain of quality-of-life assessment that is influenced by the individual's perception of his or her health status. Measurement of HRQoL can enable physicians to understand how an illness interferes with a patient's day-to-day life, improve patient-physician communication, and optimize clinical outcomes. Chronic rhinosinusitis (CRS) is one of the most common chronic diseases, affecting 14-16% of the adult US population. In addition to significant health care costs, CRS has been shown to substantially reduce HRQoL. In this review article, we discuss the definition and interpretation of HRQoL data and describe several validated rhinosinusitis HRQoL instruments. Additionally, we review how CRS functions to lower HRQoL and the effect of medical and surgical intervention on improving HRQoL status. By understanding the relationship between CRS and associated chronic conditions, clinicians can target their evaluation to problems that will maximize clinical success.

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Section: Olfactory Dysfunction In Chronic Rhinosinusitismentioning

confidence: 98%

Quality of Life in Patients with Chronic Rhinosinusitis

Rudmik

Smith

2011

Curr Allergy Asthma Rep

154

136

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“…Olfactory loss becomes increasingly significant in neurology and psychiatry (e.g., [1]) in addition to its medical relevance in otorhinolaryngology [2,3]. Diagnostics are typically obtained through widely available psychophysical olfactory tests that allow for detailed testing of olfactory function [4].…”

Section: Introductionmentioning

confidence: 99%

A short olfactory test based on the identification of three odors

2010

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Numerous psychophysical tests of olfactory function have been developed during the last 30 years. However, although most tests provide accurate results, testing typically requires time which is not available in clinical routine. The aim of the present study was to investigate results from a test based on the identification of three odors only. A total of 500 subjects (patients with olfactory loss plus healthy controls) were included. They received (1) detailed olfactory testing, and (2) the 3-item odor identification test, the so-called q-Sticks. On a group level the q-Sticks clearly separated between anosmic, hyposmic, and normosmic subjects. In addition, q-Sticks scores were significantly higher in women compared to men, and in younger compared to older subjects. With regard to a q-Sticks score of 0, the new test had a very high specificity of 96% and a moderate sensitivity of 66%. Although the q-Sticks must not be seen as a replacement of more extensive and, therefore, more accurate olfactory tests, they allow the investigator to identify anosmia with a very high specificity. Considering the test's portability, ease of administration, longevity, and possibility to be used over and over again, it can be expected to find its way into the clinician's routine or screening diagnostic armamentarium.

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“…A number of conditions can lead to quantitative and qualitative changes in chemosensory ability (Table 1). According to epidemiological studies, the prevalence of olfactory loss ranges from 19% to 24% [28][29][30], yet many people are unaware of olfactory loss and remain undiagnosed [30].…”

Section: What's New?mentioning

confidence: 99%

Association between diabetes mellitus and olfactory dysfunction: current perspectives and future directions

et al. 2017

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The increasing global prevalence of diabetes mellitus presents a significant challenge to healthcare systems today. Although diabetic retinopathy, nephropathy and neuropathy are well-established complications of diabetes, there is a paucity of research examining the impact of dysglycaemia on the olfactory system. Olfaction is an important sense, playing a role in the safety, nutrition and quality of life of an individual, but its importance is often overlooked when compared with the other senses. As a result, olfactory dysfunction is often underdiagnosed. The present review article aims to present and discuss the available evidence on the relationship between diabetes and olfaction. It also explores the associations between olfactory dysfunction and diabetes complications that could explain the underlying pathogenesis. Finally, it summarizes the putative pathological mechanisms underlying olfactory dysfunction in diabetes that require further investigation.

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Clinical experience with patients with olfactory complaints, and their quality of life

Cited by 115 publications

References 20 publications

Quality of Life in Patients with Chronic Rhinosinusitis

Quality of Life in Patients with Chronic Rhinosinusitis

A short olfactory test based on the identification of three odors

Association between diabetes mellitus and olfactory dysfunction: current perspectives and future directions

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