Clinical Evidence for GLP-1 Receptor Agonists in Alzheimer’s Disease: A Systematic Review
Yulin Liang,
Vincent Doré,
Christopher C. Rowe
et al.
Abstract:Background: Alzheimer’s disease (AD) is the most common cause of dementia. While preclinical studies have shown benefits of glucagon-like peptide 1 receptor agonists (GLP-1 RA) in targeting core AD pathology, clinical studies are limited. Objective: A systematic review was performed to evaluate GLP-1 RAs in AD for their potential to target core AD pathology and improve cognition. Methods: Searches were conducted via three different databases (PubMed, Embase, and Cochrane Library). Search terms included Medical… Show more
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