Clinical Evaluation of Synthetic Aperture Sequential Beamforming Ultrasound in Patients with Liver Tumors

Hansen, P.; Hemmsen, Martin Christian; Brandt, Andreas Hjelm; Rasmussen, Joachim; Lange, Theis; Krohn, Paul Suno; Lönn, Lars; Jensen, Jørgen Arendt; Nielsen, Michael Bachmann

doi:10.1016/j.ultrasmedbio.2014.07.008

Cited by 12 publications

(9 citation statements)

References 18 publications

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“…Requesting patients to hold their breath and lie still most likely reduced these artifacts. Some tissue motion was evident in the image sequences evaluated and no degradation of image quality was seen, which is consistent with previous findings with clinical SASB imaging (Hansen et al 2014). However, this study did not evaluate tissue motion with beamformed SASB-THI images, which should be evaluated in future clinical studies.…”

Section: Discussionsupporting

confidence: 91%

“…Scanning heavy or obese patients is more difficult, because of the thicker abdominal fat layers and higher heart rates (Hansen et al 2014). Several patients in this study were hard to scan as they had discomfort lying on their backs, an altered anatomic layout because of previous surgery, trouble holding their breath and trouble lying still.…”

Section: Discussionmentioning

confidence: 99%

“…By placing a sliding bar on a visual analogue scale (VAS) (Freyd 1923) (Fig. 3), radiologists indicated the sequence with their preferred image quality as previously described by Hansen et al (2014). The VAS ranged from 250 to 50, and positive values always favored SASB-THI, regardless of the side on which the SASB-THI image was placed.…”

Section: Image Evaluationmentioning

confidence: 99%

“…The second beamformer recombines a set of emissions to create the final high-resolution image (Hemmsen et al 2012a;Kortbek et al 2013). Previous studies have evaluated the image quality of SASB against conventional dynamic receive focusing (DRF) and reported equally good image quality, indicating that SASB is applicable to medical imaging , 2012b, Hansen et al 2014. SASB can generate an acoustic field intense enough to create harmonics for THI, and it has been suggested that these techniques be combined to improve the image quality of SASB even further.…”

Section: Introductionmentioning

confidence: 99%

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Clinical Evaluation of Synthetic Aperture Harmonic Imaging for Scanning Focal Malignant Liver Lesions

Brandt

Hemmsen

Hansen

et al. 2015

Ultrasound in Medicine & Biology

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Abstract-The purpose of the study was to perform a clinical comparison of synthetic aperture sequential beamforming tissue harmonic imaging (SASB-THI) sequences with a conventional imaging technique, dynamic receive focusing with THI (DRF-THI). Both techniques used pulse inversion and were recorded interleaved using a commercial ultrasound system (UltraView 800, BK Medical, Herlev, Denmark). Thirty-one patients with malignant focal liver lesions (confirmed by biopsy or computed tomography/magnetic resonance) were scanned. Detection of malignant focal liver lesions and preference of image quality were evaluated blinded off-line by eight radiologists. In total, 2,032 evaluations of 127 image sequences were completed. The sensitivity (77% SASB-THI, 76% DRF-THI, p 5 0.54) and specificity (71% SASB-THI, 72% DRF-THI, p 5 0.67) of detection of liver lesions and the evaluation of image quality (p 5 0.63) did not differ between SASB-THI and DRF-THI. This study indicates the ability of SASB-THI in a true clinical setting.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Section: Image Evaluationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Clinical Evaluation of Synthetic Aperture Harmonic Imaging for Scanning Focal Malignant Liver Lesions

Brandt

Hemmsen

Hansen

et al. 2015

Ultrasound in Medicine & Biology

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“…SASB reduces the amount of data transmitted by a factor of 64 compared to DRF. The reduction makes it possible to implement a SA technique in conventional ultrasound scanners, and in the future to construct wireless ultrasound transducers or tablet based ultrasound system [14]. The combination of SASB and THI has the advantage of reduced computational load, and at the same time the benefits of THI e.g.…”

Section: Discussionmentioning

confidence: 99%